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Translesion Synthesis Pathway Bioinformatics

Disease and disorder research has been conducted in relation to the Translesion Synthesis Pathway and Malignant Neoplasms, Xeroderma Pigmentosum, Xeroderma, Neoplasms, Genomic Instability. The study of the Translesion Synthesis Pathway has been mentioned in research publications which can be found using our bioinformatics tool below. The Translesion Synthesis Pathway has been researched in relation to Dna Replication, Dna Repair, Cell Cycle, Error-prone Translesion Synthesis, Mismatch Repair. The Translesion Synthesis Pathway complements our catalog of research reagents including antibodies and ELISA kits against FUS, PCNA, POLH, REV1, POLQ.

Translesion Synthesis Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Translesion Synthesis below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 601 products for the study of the Translesion Synthesis Pathway that can be applied to Chromatin Immunoprecipitation, Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NB100-565
Knockout Validated: FUS Antibody [NB100-565] - Western blot shows lysates of HEK293 human embryonic kidney parental cell line and FUS knockout (KO) HEK293 human embryonic kidney cell line. PVDF membrane was probed with 1:1000 of Rabbit Anti-Human FUS Polyclonal Antibody (Catalog # NB100-565) followed by HRP-conjugated Anti-Rabbit IgG Secondary Antibody (Catalog #HAF008). Specific band was detected for FUS at approximately 75 kDa (as indicated) in the parental HEK293 celll line, but is not detectable in the knockout HEK293 cell line. This experiment was conducted under reducing conditions.Western Blot: FUS Antibody [NB100-565] - Whole cell lysate (50 ug) from HepG2, HeLa, 293T, and mouse NIH3T3 cells prepared using NETN lysis buffer. Affinity purified rabbit anti-FUS antibody used for WB at 0.04 ug/mL. Detection: chemiluminescence with an exposure time of 10 seconds.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

     3 Reviews

18 Publications
NB500-106
Western Blot: PCNA Antibody (PC10) [NB500-106] - Whole cell protein from human HeLa, A431, mouse Neuro2A and rat PC12 cells was separated on a 4-20% gel by SDS-PAGE, transferred to 0.2 um PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 1.0 ug/mL anti-Histone h3 in block buffer and detected with an anti-mouse HRP secondary antibody using chemiluminescence.Immunocytochemistry/Immunofluorescence: PCNA Antibody (PC10) [NB500-106] - HeLa cells were fixed and permeabilized for 10 minutes using cold (-20C) MeOH. The cells were incubated with anti-PCNA [PC10] at 5 ug/mL overnight at 4C and detected with an anti-mouse IgG Dylight 488 (Green) at a 1:500 dilution. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 40X objective.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ChIP

     4 Reviews

31 Publications
NB100-60424
Western Blot: XPV/DNA polymerase eta Antibody [NB100-60424] - Detection of human PolH by western blot. Samples: Whole cell lysate (50 ug) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified Rabbit anti-PolH antibody NB100-60424 used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.Immunoprecipitation: XPV/DNA polymerase eta Antibody [NB100-60424] - Detection of human XPV/DNA polymerase eta/PolH by western blot of immunoprecipitates. Samples: Whole cell lysate (1.0 mg per IP reaction; 20% of IP loaded) from Hela cells prepared using NETN lysis buffer. Antibodies: Affinity purified Rabbit anti-PolH antibody NB100-60424 (lot 3) used for IP at 6 ug per reaction. PolH was also immunoprecipitated by a previous lot of this antibody (lot 2) and rabbit anti-PolH antibody NB100-60423. For blotting immunoprecipitated PolH, NB100-60424 was used at 0.1 ug/ml. Chemiluminescence with an exposure time of 3 minutes.

Rabbit Polyclonal
Species Human
Applications WB, IP

2 Publications
NBL1-15290
Western Blot: REV1 Overexpression Lysate (Adult Normal) [NBL1-15290] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for REV1.


Species Human

H00010721-M09
Western Blot: DNA polymerase theta Antibody (1C11) [H00010721-M09]ELISA: DNA polymerase theta Antibody (1C11) [H00010721-M09] - Detection limit for recombinant GST tagged POLQ is approximately 1ng/ml as a capture antibody.

Mouse Monoclonal
Species Human
Applications WB, ELISA, S-ELISA

     1 Review

1 Publication
NB100-56356
Western Blot: DNA polymerase sigma Antibody [NB100-56356] - Analysis of DNA polymerase sigma in HeLa cell lysate using NB100-56356 at A) 2 ug/ml and B) 5 ug/ml.

Rabbit Polyclonal
Species Human
Applications WB

H00005980-Q01
12.5% SDS-PAGE Stained with Coomassie Blue.


Species Human

H00051426-M01
Western Blot: DNA Polymerase Kappa Antibody (6F2) [H00051426-M01] - POLK monoclonal antibody (M01), clone 6F2 Analysis of POLK expression in Hela S3 NE.Immunocytochemistry/Immunofluorescence: DNA Polymerase Kappa Antibody (6F2) [H00051426-M01] - Analysis of monoclonal antibody to POLK on HeLa cell. Antibody concentration 10 ug/ml.

Mouse Monoclonal
Species Human
Applications WB, ELISA, ICC/IF

     1 Review

2 Publications
NBP2-38600
Western Blot: DNA Polymerase beta Antibody [NBP2-38600] - Lane 1: Marker  [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.  Lane 2: Human cell line RT-4Immunocytochemistry/Immunofluorescence: DNA Polymerase beta Antibody [NBP2-38600] - Staining of human cell line A-431 shows localization to vesicles. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

     1 Review

NB100-148
Western Blot: Rad51 Antibody (14B4) [NB100-148] - Various whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with Rad51 antibody [14B4] diluted at 1:500. The HRP-conjugated anti-mouse IgG antibody (NBP2-19382) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.Immunocytochemistry/Immunofluorescence: Rad51 Antibody (14B4) [NB100-148] - Staining of RAD51 nuclear foci in U2OS cells using RAD51 14B4 antibody. Cells were pre-extracted with CSK buffer before fixation with 4% PFA. RAD51 14B4 was used at 1:1000 dultion. DAPI was used to counterstain the nucleus. Scale bar, 10 mciro-meter.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ChIP, ICC/IF

     4 Reviews

48 Publications
H00056852-M01
Western Blot: RAD18 Antibody (3H7) [H00056852-M01] - Analysis of RAD18 expression in transfected 293T cell line by RAD18 monoclonal antibody (M01), clone 3H7.Lane 1: RAD18 transfected lysate(56.2 KDa).Lane 2: Non-transfected lysate.Immunocytochemistry/Immunofluorescence: RAD18 Antibody (3H7) [H00056852-M01] - The antibody was used to detect RAD18 in U2os Cells. Anti-mouse 2nd antibody was used for detection (Red). DAPI was used for nuclear staining (Blue). This image was submitted via customer Review.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ELISA, ICC/IF

     2 Reviews

13 Publications
NBP2-75562
Western Blot: MAD2L2 Antibody (JU99-23) [NBP2-75562] - Analysis of Mad2L2 on SiHa cell using anti-Mad2L2 antibody at 1/500 dilution.Immunohistochemistry-Paraffin: MAD2L2 Antibody (JU99-23) [NBP2-75562] - Analysis of paraffin-embedded rat lung tissue using anti-Mad2L2 antibody. Counter stained with hematoxylin.

Rabbit Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, IHC

NB100-81665
Immunohistochemistry: DNA Polymerase lambda Antibody [NB100-81665] - Detection of human Pol Lambda by immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti- Pol Lambda (NB100-81665). Detection: DABImmunohistochemistry-Paraffin: DNA Polymerase lambda Antibody [NB100-81665] - FFPE section of human prostate nodular hypertrophy.  NB100-81665 used at a dilution of 1:250.

Rabbit Polyclonal
Species Human, Mouse
Applications WB (-), IHC, IHC-P

NBP2-57664
Western Blot: DNA polymerase mu Antibody [NBP2-57664] - Western blot analysis in human cell line RT-4.Immunocytochemistry/Immunofluorescence: DNA polymerase mu Antibody [NBP2-57664] - Staining of human cell line U-251 MG shows localization to nucleus & cytosol.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF

NBP2-61816
Western Blot: PXR/NR1I2 Antibody (1D12G1) [NBP2-61816] - Analysis using NR1I2 mAb against human NR1I2 (AA: 1-142) recombinant protein. (Expected MW is 42.2 kDa)Immunocytochemistry/Immunofluorescence: PXR/NR1I2 Antibody (1D12G1) [NBP2-61816] - Analysis of Hela cells using NR1I2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.  Goat anti-Mouse IgG (H+L) DyLight 488 Secondary antibody was used.

Mouse Monoclonal
Species Human
Applications WB, ELISA, Flow

NBP2-54643
Flow (Cell Surface): Nectin-1/PVRL1 Antibody (R1.302) [NBP2-54643] - Surface staining of human peripheral blood with anti-human CD111 (R1.302) PE. Flow Cytometry: Nectin-1/PVRL1 Antibody (R1.302) [NBP2-54643] - Surface staining of human peripheral blood with anti-human CD111 (R1.302) purified, GAM-APC.

Mouse Monoclonal
Species Human
Applications WB, Flow, ICC/IF

NB100-175
Western Blot: DNA Polymerase iota Antibody [NB100-175] - Western blot analysis of DNA Polymerase iota in NIH-3T3 whole cell lysate.Immunocytochemistry/Immunofluorescence: DNA Polymerase iota Antibody [NB100-175] - The DNA Polymerase Iota Antibody was tested in HeLa cells at a 1:250 dilution against Dylight 488 (Green).  Alpha-tubulin and nuclei were counterstained against Dylight 550 (Red) and DAPI (Blue).

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF

4 Publications
NB100-56360
Western Blot: UEV2 Antibody [NB100-56360] - Detection of UBE2V2 in HL-60 cell lysate with anti-UBE2V2 pcAb this antibody at 2ug/ml.

Rabbit Polyclonal
Species Human
Applications WB