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Interstrand Cross-link Repair Pathway Bioinformatics

Disease and disorder research has been conducted in relation to the Interstrand Cross-link Repair Pathway and Fanconi Anemia, Anemia, Malignant Neoplasms, Neoplasms, Cytogenetic Abnormality. The study of the Interstrand Cross-link Repair Pathway has been mentioned in research publications which can be found using our bioinformatics tool below. The Interstrand Cross-link Repair Pathway has been researched in relation to Dna Repair, Hypersensitivity, Cell Cycle, Dna Replication, Aging. The Interstrand Cross-link Repair Pathway complements our catalog of research reagents including antibodies and ELISA kits against FAAP20, BRCA2, ERCC1, ERCC2, ERCC4.

Interstrand Cross-link Repair Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Interstrand Cross-link Repair below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 784 products for the study of the Interstrand Cross-link Repair Pathway that can be applied to Chromatin Immunoprecipitation, Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

FANCD2 Antibody
NB100-182
Immunocytochemistry/Immunofluorescence: FANCD2 Antibody [NB100-182] - Analysis using the Biotin conjugate of NB100-182. FancD2 colocalizes in vivo with another protein in SiHa cells after cell exposure to IR. Proliferating SiHa cells were exposed to 10 Gy of IR and double color immunofluorescence staining was performed after 8 h. Images were captured in a Kodak digital image system on a Leica fluorescence microscope.Western Blot: FANCD2 Antibody [NB100-182] - Analysis of FANCD2 in human PD20 cells. Image courtesy of anonymous customer review

Rabbit Polyclonal
Species Human, Mouse, Canine
Applications WB, Simple Western, Flow

     7 Reviews

137 Publications
ERCC1 Antibody (8F1)
NB500-704
Immunohistochemistry-Paraffin: ERCC1 Antibody (8F1) [NB500-704] - Formalin fixed paraffin embedded human tonsil stained with ERCC1 antibody.Immunohistochemistry-Paraffin: ERCC1 Antibody (8F1) [NB500-704] - Analysis of ERCC1 in human non-small cell lung cancer. Image courtesy of product review submitted by Alex Soltermann.

Mouse Monoclonal
Species Human, Rat, Chinese Hamster
Applications WB, ICC/IF, IHC

     1 Review

15 Publications
SNM1 Antibody
NBP1-89663
Immunocytochemistry: SNM1 Antibody [NBP1-89663] - Staining of human cell line A-431 shows positivity in nucleus and nucleoli.Immunohistochemistry-Paraffin: SNM1 Antibody [NBP1-89663] - Staining of human placenta shows strong nuclear positivity in trophoblastic cells.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

FACA/FANCA Antibody
NB100-2564
Western Blot: FACA/FANCA Antibody [NB100-2564] - Detection of FANC A in transfected COS1 cell lysate.

Rabbit Polyclonal
Species Human
Applications WB

1 Publication
PCNA Antibody (PC10)
NB500-106
Western Blot: PCNA Antibody (PC10) [NB500-106] - Whole cell protein from human HeLa, A431, mouse Neuro2A and rat PC12 cells was separated on a 4-20% gel by SDS-PAGE, transferred to 0.2 um PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 1.0 ug/mL anti-Histone h3 in block buffer and detected with an anti-mouse HRP secondary antibody using chemiluminescence.Immunocytochemistry/Immunofluorescence: PCNA Antibody (PC10) [NB500-106] - HeLa cells were fixed and permeabilized for 10 minutes using cold (-20C) MeOH. The cells were incubated with anti-PCNA [PC10] at 5 ug/mL overnight at 4C and detected with an anti-mouse IgG Dylight 488 (Green) at a 1:500 dilution. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 40X objective.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ChIP

     4 Reviews

24 Publications
BRIP1/FANCJ Antibody
NB100-416
Western Blot: BRIP1/FANCJ Antibody [NB100-416] - Analysis on MCF7, HeLa, 293T and SKOV3 crude cell lysates.Immunohistochemistry: BRIP1/FANCJ Antibody [NB100-416] - Analysis of BRIP1/FANCJ in human colon and rectum tissues. Image courtesy of an anonymous customer review.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IB, ICC/IF

     4 Reviews

10 Publications
XPF Antibody (OTI4E11)
NBP2-01020
Western Blot: XPF Antibody (4E11) [NBP2-01020] Analysis of extracts (35ug) from 9 different cell lines by using anti-XPF monoclonal antibody.Immunocytochemistry/Immunofluorescence: XPF Antibody (4E11) [NBP2-01020] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY XPF.

Mouse Monoclonal
Species Human, Mouse
Applications WB, Flow, ICC/IF

LXR beta/NR1H2 Antibody
NB100-74457
Western Blot: LXR beta/NR1H2 Antibody [NB100-74457] - 25 ug of rat liver (Lane 1), mouse liver (Lane 2) and Hela (Lane 3) cell lysates.Immunocytochemistry/Immunofluorescence: LXR beta/NR1H2 Antibody [NB100-74457] - Analysis of LXR beta (green) showing positive staining in the nuclear envelope of C2C12 cells (right) compared with a negative control in the absence of primary antibody (left).

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF

2 Publications
DCLRE1B Antibody (OTI2B7)
NBP2-03563
Western Blot: DCLRE1B Antibody (2B7) [NBP2-03563] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DCLRE1B (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DCLRE1B.Immunohistochemistry-Paraffin: DCLRE1B Antibody (2B7) [NBP2-03563] Staining of paraffin-embedded Human endometrium tissue using anti-DCLRE1B mouse monoclonal antibody.

Mouse Monoclonal
Species Human
Applications WB, Flow, IHC

DNA polymerase theta Antibody (1C11)
H00010721-M09
Western Blot: DNA polymerase theta Antibody (1C11) [H00010721-M09]ELISA: DNA polymerase theta Antibody (1C11) [H00010721-M09] - Detection limit for recombinant GST tagged POLQ is approximately 1ng/ml as a capture antibody.

Mouse Monoclonal
Species Human
Applications WB, ELISA

     1 Review

Fascin Antibody (833223) [Unconjugated]
MAB7745
Western blot shows lysates of HeLa human cervical epithelial carcinoma cell line, K562 human chronic myelogenous leukemia cell line, Neuro‑2A mouse neuroblastoma cell line, and Rat‑2 rat embryonic fibroblast cell line. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human Fascin Monoclonal Antibody (Catalog # MAB7745) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # <A class=NoLineLink href=Simple Western lane view shows lysates of HeLa human cervical epithelial carcinoma cell line, loaded at 0.5 mg/mL. A specific band was detected for Fascin at approximately 61 kDa (as indicated) using 10 µg/mL of Mouse Anti-Human Fascin Monoclonal Antibody (Catalog # MAB7745). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.

Mouse Monoclonal
Species Human
Applications WB, Simple Western, IHC

     2 Reviews

FUS Antibody
NBP1-89113
Western Blot: FUS Antibody [NBP1-89113] - Analysis in U-251MG cells transfected with control siRNA, target specific siRNA probe #1 and #2, using anti-FUS antibody. Remaining relative intensity is presented. Loading control: anti-GAPDH.Immunocytochemistry/Immunofluorescence: FUS Antibody [NBP1-89113] - Staining of human cell line U-251 MG shows localization to nucleoplasm. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

     1 Review

19 Publications
MTMR15 Antibody
NBP1-42677
Western Blot: MTMR15 Antibody [NBP1-42677] - Whole cell lysate (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-MTMR15 antibody used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. MTMR15 was also immunoprecipitated by another rabbit anti-MTMR15 antibody, which recognizes a downstream epitope.Immunohistochemistry-Paraffin: MTMR15 Antibody [NBP1-42677] - FFPE section of human ovarian carcinoma. Antibody used at a dilution of 1:250 Detection: DAB staining using Immunohistochemistry Accessory Kit.

Rabbit Polyclonal
Species Human
Applications WB, IHC-P, IP

     1 Review

Rad51 Antibody (14B4)
NB100-148
Western Blot: Rad51 Antibody (14B4) [NB100-148] - Various whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with Rad51 antibody [14B4] diluted at 1:500. The HRP-conjugated anti-mouset IgG antibody (NBP2-19382) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.Immunocytochemistry/Immunofluorescence: Rad51 Antibody (14B4) [NB100-148] - staning of RAD51 nuclear foci in U2OS cells using RAD51 14B4 antibody. Cells were pre-extracted with CSK buffer before fixation with 4% PFA. RAD51 14B4 was used at 1:1000 dultion. DAPI was used to counterstain the nucleus. Scale bar, 10 mciro-meter.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ChIP, ICC/IF

     3 Reviews

38 Publications
BRCA2 Antibody (234403)
MAB2476
Western blot shows lysates of Capan‑1 human pancreatic adenocarcinoma cell line, HeLa human cervical epithelial carcinoma cell line, and U2OS human osteosarcoma cell line. PVDF membrane was probed with 0.2 µg/mL of Human BRCA2 Monoclonal Antibody (Catalog # MAB2476) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # <a class=

Mouse Monoclonal
Species Human
Applications WB, IHC

6 Publications
XPA Antibody
NB100-93321
Western Blot: XPA Antibody [NB100-93321] - Detection of Human XPA by Western Blot. Samples: Whole cell lysate (5, 15 and 50 ug) from HeLa, cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-XPA antibody NB100-93321 used for WB at 0.04 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.Immunohistochemistry: XPA Antibody [NB100-93321] - Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti- XPA used at a dilution of 1:1,000 (0.2ug/ml). Detection: DAB

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

Frataxin Antibody (OTI1C12)
NBP2-01743
Western Blot: Frataxin Antibody (1C12) [NBP2-01743] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY Frataxin (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-Frataxin.Immunocytochemistry/Immunofluorescence: Frataxin Antibody (1C12) [NBP2-01743] Staining of COS7 cells transiently transfected by pCMV6-ENTRY Frataxin.

Mouse Monoclonal
Species Human
Applications WB, Flow, ICC/IF

XPD Antibody
AF3296
Western blot shows lysates of K562 human chronic myelogenous leukemia cell line, CH-1 mouse B cell lymphoma cell line, and Rat-2 rat embryonic fibroblast cell line. PVDF membrane was probed with 0.5 µg/mL of Human/Mouse/Rat XPD Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3296) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB

1 Publication
ID1 Antibody (JM92-13)
NBP2-66897
Western Blot: ID1 Antibody (JM92-13) [NBP2-66897] - Analysis of Id1 on 293T cell using anti-Id1 antibody at 1/1,000 dilution.Immunocytochemistry/Immunofluorescence: ID1 Antibody (JM92-13) [NBP2-66897] - Staining Id1 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Rabbit Monoclonal
Species Human
Applications WB, Flow, ICC/IF