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Interkinetic Nuclear Migration Pathway Bioinformatics

Interkinetic nuclear migration is a phenomenon that occurs during the development of neuroepithelia, which are tissues made from neuroepithelial progenitor cells. Mitosis of these cells in order to generate more tissue occurs on the ventricular surface, or apical side, of the cells. The nuclei of these cells are able to move from the basal to apical sides of the cell and vice versa, and they do so during the cell cycle in order to be in the correct location during each separate phase. Defects in the process of interkinetic nuclear migration can lead to problems with neurogenesis as well as an unfavorable ratio of neuroepithelial progenitor cell fates.

Interkinetic Nuclear Migration Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Interkinetic Nuclear Migration below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 956 products for the study of the Interkinetic Nuclear Migration Pathway that can be applied to Western Blot, Chromatin Immunoprecipitation, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NBP1-87769
Western Blot: LIS1 Antibody [NBP1-87769] - Lane 1: Marker  [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG spImmunocytochemistry/Immunofluorescence: LIS1 Antibody [NBP1-87769] - Immunofluorescent staining of human cell line U-251 MG shows localization to centrosome.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

     2 Reviews

NB300-750
Western Blot: Pax6 Antibody [NB300-750] - Analysis of sheep retinal extractImmunocytochemistry: Pax6 Antibody [NB300-750] - ARPE-19 monolayer on glass substrate. Fixative Methanol Blocking Goat Serum. Dilution 1:100. Incubation 1h @ RT. This image was submitted via customer Review.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

     4 Reviews

4 Publications
NBP1-84190
Immunohistochemistry-Paraffin: Nesprin 2 Antibody [NBP1-84190] - Staining of human colon.Immunohistochemistry-Paraffin: Nesprin 2 Antibody [NBP1-84190] - Staining of human cerebral cortex, colon, kidney and testis using Anti-SYNE2 antibody NBP1-84190 (A) shows similar protein distribution across tissues to independent antibody NBP2-38620 (B).

Rabbit Polyclonal
Species Human, Rat
Applications WB, IHC, IHC-P

2 Publications
NB500-106
Western Blot: PCNA Antibody (PC10) [NB500-106] - Whole cell protein from human HeLa, A431, mouse Neuro2A and rat PC12 cells was separated on a 4-20% gel by SDS-PAGE, transferred to 0.2 um PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 1.0 ug/mL anti-Histone h3 in block buffer and detected with an anti-mouse HRP secondary antibody using chemiluminescence.Immunocytochemistry/Immunofluorescence: PCNA Antibody (PC10) [NB500-106] - HeLa cells were fixed and permeabilized for 10 minutes using cold (-20C) MeOH. The cells were incubated with anti-PCNA [PC10] at 5 ug/mL overnight at 4C and detected with an anti-mouse IgG Dylight 488 (Green) at a 1:500 dilution. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 40X objective.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ChIP

     4 Reviews

27 Publications
NBP2-75679
Western Blot: SYNE1 Antibody (JB35-26) [NBP2-75679] - Analysis of Nesprin 1 on different lysates using anti-Nesprin 1 antibody at 1/500 dilution.Positive control:Lane 1: A549      Lane 2: Mouse spleen tissueImmunocytochemistry/Immunofluorescence: SYNE1 Antibody (JB35-26) [NBP2-75679] - Staining Nesprin 1 in C2C12 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Rabbit Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

NB300-223
Immunocytochemistry/Immunofluorescence: Vimentin Antibody [NB300-223] - Human A7 cells. Cells were fixed with 10% formalin and permeabilized with 0.1% TritonX-100. After blocking, cells were incubated with primary antibody (1:600) at 4C O/N followed with Alexa Fluor 488 labeled secondary antibody and counterstained with DAPI and Phalloidin for nuclei and F-actin respectively. Imaged with Leica TCS SP5 confocal microscope. Image from verified customer review.Immunohistochemistry-Frozen: Vimentin Antibody [NB300-223] - 10 um Cryosections from PFA fixed murine brain acute slices stained with Vimentin antibody (1:600) and Alexa Fluor 488 anti chicken IgG. Antibody showed specific staining, also of blood vessels. Image from verified customer review.

Chicken Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

     5 Reviews

33 Publications
NBP2-49011
Immunohistochemistry: CEP120 Antibody [NBP2-49011] - Staining of human spleen shows strong cytoplasmic positivity in cells in red pulp.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

NBP1-86960
Western Blot: LEF1 Antibody [NBP1-86960] - Analysis in control (vector only transfected HEK293T lysate) and LEF1 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).Immunocytochemistry/Immunofluorescence: LEF1 Antibody [NBP1-86960] - Staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

1 Publication
NB400-148
Knockout Validated: Niemann-Pick C1 Antibody [NB400-148] - Western blot shows lysates of HeLa human cervical epithelial carcinoma parental cell line and NPC1 knockout (KO) HeLa cell line. PVDF membrane was probed with 1:1000 of Rabbit Anti-Human NPC1 Polyclonal Antibody (Catalog # NB400-148) followed by HRP-conjugated Anti-Rabbit IgG Secondary Antibody (Catalog #HAF008). Specific band was detected for NPC1 at approximately 240-260 kDa (as indicated) in the parental HeLa cell line, but is not detectable in the knockout HeLa cell line. This experiment was conducted under reducing conditions.Western Blot: Niemann-Pick C1 Antibody [NB400-148] - HeLa lysate, BHK lysate, A431 lysate tested at 1:1000. Image from verified customer review.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, EM, ICC/IF

     5 Reviews

34 Publications
NB100-1768
Western Blot: Chk1 Antibody (2G1D5) [NB100-1768] - Analysis using Chk1 mouse mAb against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY Chk1 cDNA (2).Immunocytochemistry/Immunofluorescence: Chk1 Antibody (2G1D5) [NB100-1768] - Chk1 antibody was tested at 1:10 in HeLa cells with DyLight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). Image objective 40X.

Mouse Monoclonal
Species Human
Applications WB, ICC/IF, IHC

NBP2-34104
Immunohistochemistry-Paraffin: NUMBL Antibody [NBP2-34104] - Staining of human cerebral cortex shows moderate cytoplasmic positivity in a few neuronal cells.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

NBP2-75696
Western Blot: UNC84B Antibody (JG39-52) [NBP2-75696] - Analysis of SUN2 on rat kidney tissue lysate using anti-SUN2 antibody at 1/2,000 dilution.Immunocytochemistry/Immunofluorescence: UNC84B Antibody (JG39-52) [NBP2-75696] - Staining SUN2 (green) in SK-Br-3 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Rabbit Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

NBP1-87396
Immunocytochemistry/Immunofluorescence: SUN1 Antibody [NBP1-87396] - Staining of human cell line A-431 shows positivity in nuclear membrane. Antibody staining is shown in green.Immunohistochemistry-Paraffin: SUN1 Antibody [NBP1-87396] - Staining of human colon.

Rabbit Polyclonal
Species Human
Applications WB, Simple Western, ICC/IF

9 Publications
NBP2-13957
Western Blot: ELSPBP1 Antibody [NBP2-13957] - Analysis in control (vector only transfected HEK293T lysate) and ELSPBP1 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).Immunohistochemistry-Paraffin: ELSPBP1 Antibody [NBP2-13957] - Staining in human epididymis and endometrium tissues using anti-ELSPBP1 antibody. Corresponding ELSPBP1 RNA-seq data are presented for the same tissues.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NBP1-76526
Western Blot: Axin-2 Antibody [NBP1-76526] - Mouse lung lysate at 1 ug/mL.Immunohistochemistry: Axin-2 Antibody [NBP1-76526] -  Mouse lung tissue antibody at 5 ug/mL.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ELISA, IHC

248-BDB
2 μg/lane of Recombinant Human BDNF was resolved with SDS-PAGE underreducing (R) and non-reducing (NR) conditions and visualized by Coomassie® Bluestaining, showing bands at 13-14 kDa and 11-12 kDa, respectively.    Recombinant Human  BDNF (Catalog #    248-BDB) stimulates cell proliferation in  the BaF mouse pro-B cell line transfected with TrkB. The ED<sub>50</sub> for this effect is 0.2‑2 ng/mL.


Species Human, Mouse, Rat

127 Publications

Related Genes

The Interkinetic Nuclear Migration Pathway has been researched against:

Related PTMs

The Interkinetic Nuclear Migration Pathway has been studied in relation to posttranslational modifications (PTMs) including: