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Interkinetic Nuclear Migration Pathway Bioinformatics

Interkinetic nuclear migration is a phenomenon that occurs during the development of neuroepithelia, which are tissues made from neuroepithelial progenitor cells. Mitosis of these cells in order to generate more tissue occurs on the ventricular surface, or apical side, of the cells. The nuclei of these cells are able to move from the basal to apical sides of the cell and vice versa, and they do so during the cell cycle in order to be in the correct location during each separate phase. Defects in the process of interkinetic nuclear migration can lead to problems with neurogenesis as well as an unfavorable ratio of neuroepithelial progenitor cell fates.

Interkinetic Nuclear Migration Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Interkinetic Nuclear Migration below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 737 products for the study of the Interkinetic Nuclear Migration Pathway that can be applied to Western Blot, Chromatin Immunoprecipitation, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NBP1-87769
Western Blot: LIS1 Antibody [NBP1-87769] - Lane 1: Marker  [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG spImmunocytochemistry/Immunofluorescence: LIS1 Antibody [NBP1-87769] - Immunofluorescent staining of human cell line U-251 MG shows localization to centrosome.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

     2 Reviews

NB300-750
Western Blot: Pax6 Antibody [NB300-750] - Analysis of sheep retinal extractImmunocytochemistry: Pax6 Antibody [NB300-750] - ARPE-19 monolayer on glass substrate. Fixative Methanol Blocking Goat Serum. Dilution 1:100. Incubation 1h @ RT. This image was submitted via customer Review.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IP

     4 Reviews

2 Publications
NBP2-59944
Western Blot: Nesprin 2 Antibody (6C11) [NBP2-59944] - HEK293 cells transiently expressing either GFP alone or GFP fused a small Nesp2 isoform (Nesp2a2DKASH) lacking the C-terminal KASH domain. This small isoform contains the ~180 residue Nesp2 polypeptide that was employed in the immunogen. Total cell lysates were analyzed by western blot employing either a rabbit anti-GFP or culture supernatant from three independent anti-Nesp2 hybridoma clones (6C11, 10H8 and 5C3)Immunocytochemistry/Immunofluorescence: Nesprin 2 Antibody (6C11) [NBP2-59944] - Immunofluorescence microscopy of HeLa cells. The antibodies can be used on either formaldehyde- or methanol-fixed cells.

Mouse Monoclonal
Species Human
Applications WB, ICC/IF

PPS046
Western blot of rat hippocampal lysate showing specific immunolabeling of the approximately 43 kDa Connexin 43/GJA1 phosphorylated at S368 (Control). The phosphospecificity of this labeling is demonstrated by treatment with 1200 units of lambda phosphatase ( lambda  Phosphatase) for 30 minutes before being exposed to the Anti-Phospho-Connexin 43/GJA1 (S368). The immunolabeling of Connexin43 is completely eliminated by treatment with  lambda  PPase.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB

     1 Review

1 Publication
NB500-106
Western Blot: PCNA Antibody (PC10) [NB500-106] - Analysis of human (HeLa lysate), murine (SV-T2 lysate), bovine (BAEC lysate), and porcine (PAE lysate) cell extracts.Immunohistochemistry: PCNA Antibody (PC10) [NB500-106] - Analysis of PCNA in mouse cornea. Image courtesy of product review by Bo-Yie Chen.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ChIP

     4 Reviews

22 Publications
NBP1-89349
Immunocytochemistry/Immunofluorescence: SYNE1 Antibody [NBP1-89349] - Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & nuclear membrane.Immunohistochemistry-Paraffin: SYNE1 Antibody [NBP1-89349] - Staining of human skeletal muscle shows strong cytoplasmic and nuclear membranous positivity in myocytes.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

1 Publication
NB300-223
Immunocytochemistry/Immunofluorescence: Vimentin Antibody [NB300-223] - View of mixed neuron/glial cultures stained with NB300-223 (green) and  rabbit antibody to GFAP antibody NB300-141(red). Vimentin is expressed alone in fibroblastic and endothelial cells, which are the flattened cells in the middle of the image which appear green. Astrocytes may express primarily GFAP, or GFAP and vimentin, and so appear red (GFAP only) or golden yellow (GFAP and Vimentin). In cells which express both GFAP and vimentin, the two protein assemble to produce heteropolymer filaments.Western Blot: Vimentin Antibody [NB300-223] - Western blot of crude extract of human embryonic kidney Hek293 cells stained with NB300-223, showing a single strong clean band at approx. 50kDa.

Chicken Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

     1 Review

19 Publications
NBP2-49011
Immunohistochemistry: CEP120 Antibody [NBP2-49011] - Staining of human spleen shows strong cytoplasmic positivity in cells in red pulp.

Rabbit Polyclonal
Species Human
Applications IHC

NBP1-86960
Western Blot: LEF1 Antibody [NBP1-86960] - Analysis in human cell lines SK-MEL-30 and A-549 using Anti-LEF1 antibody. Corresponding LEF1 RNA-seq data are presented for the same cell lines. Loading control: Anti-PPIB.Immunohistochemistry-Paraffin: LEF1 Antibody [NBP1-86960] - Staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

1 Publication
NB400-148
Western Blot: Niemann-Pick C1 Antibody [NB400-148] - Hela lysate, BHK lysate, A431 lysate tested at 1:1000. Image provided by verified customer review.Immunocytochemistry/Immunofluorescence: Niemann-Pick C1 Antibody [NB400-148] - HeLa cells were fixed and permeabilized for 10 minutes using -20C MeOH. The cells were incubated with anti-Niemann-Pick C1 at 5 ug/ml overnight at 4C and detected with an anti-rabbit Dylight 488 (Green) at a 1:500 dilution. Alpha tubulin (DM1A) NB100-690 was used as a co-stain at a 1:1000 dilution and detected with an anti-mouse Dylight 550 (Red) at a 1:500 dilution. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 40X objective.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, EM, ICC/IF

     3 Reviews

33 Publications
NB100-464
Western Blot: Chk1 Antibody [NB100-464] - Detection of Human Chk1 by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa, 293T, Jurkat, and mouse TMCK cells. Antibodies: Affinity purified rabbit anti-Chk1 antibody NB100-464 used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.Immunocytochemistry/Immunofluorescence: Chk1 Antibody [NB100-464] - NBF-fixed HeLa cells treated with neocarzinostatin. Antibody used at a dilution of 1:1,000 (1ug/ml).

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

5 Publications
NBP2-34104
Immunohistochemistry-Paraffin: NUMBL Antibody [NBP2-34104] - Staining of human cerebral cortex shows moderate cytoplasmic positivity in a few neuronal cells.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

NBP2-59942
Western Blot: UNC84B Antibody (3.1E) [NBP2-59942] - Analysis of heart tissue lysates derived from SUN2+/- and SUN2-/- mice.Immunocytochemistry/Immunofluorescence: UNC84B Antibody (3.1E) [NBP2-59942] - Adult fibroblasts derived from SUN2+/- and SUN2-/- mice. Cells were labeled with the 3.1E monoclonal antibody against SUN2. This antibody can be used on either formaldehyde- or methanol-fixed cells.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF

NBP1-87396
Immunocytochemistry/Immunofluorescence: SUN1 Antibody [NBP1-87396] - Staining of human cell line A-431 shows positivity in nuclear membrane.Immunohistochemistry-Paraffin: SUN1 Antibody [NBP1-87396] - Staining of human placenta shows strong nuclear membrane positivity in trophoblastic cells.

Rabbit Polyclonal
Species Human
Applications WB, Simple Western, ICC/IF

9 Publications
NBP2-13958
Immunohistochemistry-Paraffin: ELSPBP1 Antibody [NBP2-13958] - Staining of human epididymis shows membranous positivity in glandular cells.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

NBP1-76526
Western Blot: Axin-2 Antibody [NBP1-76526] - Mouse lung lysate at 1 ug/mL.Immunocytochemistry/Immunofluorescence: Axin-2 Antibody [NBP1-76526] - Rat Lung cells  with AXIN-2 antibody at 20 ug/mL

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ELISA, ICC/IF

248-BD/CF
1 μg/lane of Recombinant Human BDNF was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 13 kDa.Recombinant Human BDNF (Catalog #<br>248‑BD/CF) stimulates cell proliferation in the BaF mouse pro-B cell line transfected with TrkB. The ED<sub>50</sub> for this effect is 0.2-2 ng/mL.


Species Human, Mouse, Rat

77 Publications

Related Genes

The Interkinetic Nuclear Migration Pathway has been researched against:

Related PTMs

The Interkinetic Nuclear Migration Pathway has been studied in relation to posttranslational modifications (PTMs) including: