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Interkinetic Nuclear Migration Pathway Bioinformatics

Interkinetic nuclear migration is a phenomenon that occurs during the development of neuroepithelia, which are tissues made from neuroepithelial progenitor cells. Mitosis of these cells in order to generate more tissue occurs on the ventricular surface, or apical side, of the cells. The nuclei of these cells are able to move from the basal to apical sides of the cell and vice versa, and they do so during the cell cycle in order to be in the correct location during each separate phase. Defects in the process of interkinetic nuclear migration can lead to problems with neurogenesis as well as an unfavorable ratio of neuroepithelial progenitor cell fates.

Interkinetic Nuclear Migration Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Interkinetic Nuclear Migration below! For more information on how to use Laverne, please read the How to Guide.
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Top Research Reagents

We have 827 products for the study of the Interkinetic Nuclear Migration Pathway that can be applied to Western Blot, Chromatin Immunoprecipitation, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NBP1-87769
Western Blot: LIS1 Antibody [NBP1-87769] - Lane 1: Marker  [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG spImmunocytochemistry/Immunofluorescence: LIS1 Antibody [NBP1-87769] - Immunofluorescent staining of human cell line U-251 MG shows localization to centrosome.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

     2 Reviews

NB300-750
Western Blot: Pax6 Antibody [NB300-750] - Analysis of sheep retinal extractImmunocytochemistry: Pax6 Antibody [NB300-750] - ARPE-19 monolayer on glass substrate. Fixative Methanol Blocking Goat Serum. Dilution 1:100. Incubation 1h @ RT. This image was submitted via customer Review.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IP

     4 Reviews

2 Publications
NBP2-59944
Western Blot: Nesprin 2 Antibody (6C11) [NBP2-59944] - HEK293 cells transiently expressing either GFP alone or GFP fused a small Nesp2 isoform (Nesp2a2DKASH) lacking the C-terminal KASH domain. This small isoform contains the ~180 residue Nesp2 polypeptide that was employed in the immunogen. Total cell lysates were analyzed by western blot employing either a rabbit anti-GFP or culture supernatant from three independent anti-Nesp2 hybridoma clones (6C11, 10H8 and 5C3)Immunocytochemistry/Immunofluorescence: Nesprin 2 Antibody (6C11) [NBP2-59944] - Immunofluorescence microscopy of HeLa cells. The antibodies can be used on either formaldehyde- or methanol-fixed cells.

Mouse Monoclonal
Species Human
Applications WB, ICC/IF

NB500-106
Western Blot: PCNA Antibody (PC10) [NB500-106] - Whole cell protein from human HeLa, A431, mouse Neuro2A and rat PC12 cells was separated on a 4-20% gel by SDS-PAGE, transferred to 0.2 um PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 1.0 ug/ml anti-Histone h3 in block buffer and detected with an anti-mouse HRP secondary antibody using chemiluminescence.Immunocytochemistry/Immunofluorescence: PCNA Antibody (PC10) [NB500-106] - HeLa cells were fixed and permeabilized for 10 minutes using -20C MeOH. The cells were incubated with anti-PCNA [PC10] at 5 ug/ml overnight at 4C and detected with an anti-mouse IgG Dylight 488 (Green) at a 1:500 dilution. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 40X objective.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ChIP

     4 Reviews

23 Publications
NBP2-59946
Western Blot: SYNE1 Antibody (9F10) [NBP2-59946] - HEK293 cells transiently expressing GFP alone, GFP fused to a small Nesp2 isoform (Nesp2a1) or to a Nesp1 isoform (Nesp1a). The small Nesp1 isoform contains the ~300 residue Nesp1 polypeptide that was employed in the immunogen. Total cell lysates were analyzed by western blot employing either a rabbit anti-GFP or culture supernatant from the anti-Nesp1 hybridoma clone (9F10). The antibody is specific for Nesp1.Immunocytochemistry/Immunofluorescence: SYNE1 Antibody (9F10) [NBP2-59946] - C2C12 cell labeled with the 9F10 monoclonal antibody (green) raised against mouse Nesp1. DNA within the nucleus (blue) is revealed by DAPI-staining.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF

NB300-223
Immunocytochemistry/Immunofluorescence: Vimentin Antibody [NB300-223] - analysis of HeLa cell culture stained with chicken pAb to vimentin, NB300-223, dilution 1:10,000 in green, and costained with EnCor mouse mAb to actin, dilution 1:500 in red. The blue is DAPI staining of nuclear DNA. The vimentin antibody stains the intermediate filament network while the actin antibody labels the submembranous cytoskeleton, stress fibers, and bundles of actin associated with cell adhesion sites.Vimentin Antibody [NB300-223] - Analysis of tissue and cell lysates using chicken pAb to Vimentin, NB300-223, dilution 1:5,000 in red. [1] protein standard (red), [2] rat whole brain lysate, [3] HeLa, [4] SH-SY5Y, [5] HEK293, and [6] NIH-3T3 cell lysates. NB300-223 binds to the vimentin protein showing a single band at ~50 kDa. The blot was simultaneously probed with mouse mAb to MAP2C/D, dilution 1:5,000 in green, revealing multiple bands around 280kDa that correspond to full length MAP2A/2B isotypes, and ~70kDa bands which are MAP2C/D isotypes. MAP2 isotypes are seen only in extracts containing neuronal lineage cells.

Chicken Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, ICC

     1 Review

22 Publications
NBP2-49011
Immunohistochemistry: CEP120 Antibody [NBP2-49011] - Staining of human spleen shows strong cytoplasmic positivity in cells in red pulp.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

NBP1-86960
Western Blot: LEF1 Antibody [NBP1-86960] - Analysis in human cell lines SK-MEL-30 and A-549 using anti-LEF1 antibody. Corresponding LEF1 RNA-seq data are presented for the same cell lines. Loading control: anti-PPIB.Immunocytochemistry/Immunofluorescence: LEF1 Antibody [NBP1-86960] - Staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

1 Publication
NB400-148
Western Blot: Niemann-Pick C1 Antibody [NB400-148] - Hela lysate, BHK lysate, A431 lysate tested at 1:1000. Image provided by verified customer review.Immunocytochemistry/Immunofluorescence: Niemann-Pick C1 Antibody [NB400-148] - HeLa cells were fixed and permeabilized for 10 minutes using -20C MeOH. The cells were incubated with anti-Niemann-Pick C1 at 5 ug/ml overnight at 4C and detected with an anti-rabbit Dylight 488 (Green) at a 1:500 dilution. Alpha tubulin (DM1A) NB100-690 was used as a co-stain at a 1:1000 dilution and detected with an anti-mouse Dylight 550 (Red) at a 1:500 dilution. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 40X objective.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, EM, ICC/IF

     3 Reviews

33 Publications
NB100-1768
Western Blot: Chk1 Antibody (2G1D5) [NB100-1768] - Western blot analysis using Chk1 mouse mAb against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY Chk1 cDNA (2).Immunocytochemistry/Immunofluorescence: Chk1 Antibody (2G1D5) [NB100-1768] - Chk1 antibody was tested at 1:10 in HeLa cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). Image objective 40x.

Mouse Monoclonal
Species Human
Applications WB, ICC/IF, IHC

NBP2-34104
Immunohistochemistry-Paraffin: NUMBL Antibody [NBP2-34104] - Staining of human cerebral cortex shows moderate cytoplasmic positivity in a few neuronal cells.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

NBP2-59942
Western Blot: UNC84B Antibody (3.1E) [NBP2-59942] - Analysis of heart tissue lysates derived from SUN2+/- and SUN2-/- mice.Immunocytochemistry/Immunofluorescence: UNC84B Antibody (3.1E) [NBP2-59942] - Adult fibroblasts derived from SUN2+/- and SUN2-/- mice. Cells were labeled with the 3.1E monoclonal antibody against SUN2. This antibody can be used on either formaldehyde- or methanol-fixed cells.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF

NBP1-87396
Immunocytochemistry/Immunofluorescence: SUN1 Antibody [NBP1-87396] - Staining of human cell line A-431 shows positivity in nuclear membrane. Antibody staining is shown in green. Immunohistochemistry-Paraffin: SUN1 Antibody [NBP1-87396] - Staining of human skin shows high expression.

Rabbit Polyclonal
Species Human
Applications WB, Simple Western, ICC/IF

9 Publications
NBP2-13957
Immunohistochemistry-Paraffin: ELSPBP1 Antibody [NBP2-13957] - Staining of human epididymis shows high expression.Immunohistochemistry-Paraffin: ELSPBP1 Antibody [NBP2-13957] - Staining of human epididymis shows strong cytoplasmic positivity in glandular cells.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

NBP1-76526
Western Blot: Axin-2 Antibody [NBP1-76526] - Mouse lung lysate at 1 ug/mL.Immunocytochemistry/Immunofluorescence: Axin-2 Antibody [NBP1-76526] - Rat Lung cells  with AXIN-2 antibody at 20 ug/mL

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ELISA, ICC/IF

248-BD
1 μg/lane of Recombinant Human BDNF was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 13 kDa.Recombinant Human BDNF (Catalog #<br>248‑BD) stimulates cell proliferation in the BaF mouse pro-B cell line transfected with TrkB. The ED<sub>50</sub> for this effect is 0.2-2 ng/mL.


Species Human, Mouse, Rat

     6 Reviews

98 Publications

Related Genes

The Interkinetic Nuclear Migration Pathway has been researched against:

Related PTMs

The Interkinetic Nuclear Migration Pathway has been studied in relation to posttranslational modifications (PTMs) including: