X-linked Lissencephaly is an inherited disease in which the cerebral cortex, which should normally have grooves and folds, is smooth. This abnormally smooth surface of the brain causes patients who have X-linked Lissencephaly to have mental and developmental problems, muscle weakness, seizures, and other problems. A more severe case of this disease involves the above symptoms as well as ambiguous genitalia. X-linked Lissencephaly is caused by a mutation on the ARX gene on the X-chromosome. Because it is an X-linked disease, patients with X-linked Lissencepaly are predominantly male. People are diagnosed with X-linked Lissencephaly as infants. There is currently no cure for this disease, and as a result, patients often die at a young age.
X-linked Lissencephaly Bioinformatics Tool
Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on X-linked Lissencephaly below!
For more information on how to use Laverne, please read the How to Guide.
We have 376 products for the study of X-linked Lissencephaly that can be applied to Flow Cytometry, Western Blot, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.