Von Willebrand Disease is a genetic bleeding disorder. The disease occurs when a blood clotting protein, called the von Willebrand Factor, is defected or absent from an individual. This means that individuals with von Willebrand Disease take longer to stop bleeding and form blood clots. The intensity of symptoms vary between individuals, though the most common symptom of von Willebrand Disease is abnormal bleeding. Other common symptoms include frequent nosebleeds, bleeding from gums, easy bruising, and excessive or uncontrolled bleeding. Von Willebrand Disease often has an autosomal dominant inheritance pattern, but the more severe forms are autosomal recessive. Most individuals with von Willebrand Disease have mild symptoms, so diagnosis of the disease can be difficult. Doctors often take blood tests measuring the levels of von Willebrand factor and the ability of the protein to clot. A variety of treatment options are available depending on the severity of the disease in each individual.
Von Willebrand Disease Bioinformatics Tool
Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Von Willebrand Disease below!
For more information on how to use Laverne, please read the How to Guide.
We have 1985 products for the study of Von Willebrand Disease that can be applied to Chromatin Immunoprecipitation, Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.