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Spastic Ataxia, Charlevoix-saguenay Type: Disease Bioinformatics

Research of Spastic Ataxia, Charlevoix-saguenay Type has been linked to Ataxia, Muscle Spasticity, Cerebellar Ataxia, Ataxia, Spinocerebellar, Atrophy. The study of Spastic Ataxia, Charlevoix-saguenay Type has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Spastic Ataxia, Charlevoix-saguenay Type include Dna Repair, Myelination, Protein Folding, Pathogenesis, Transport. These pathways complement our catalog of research reagents for the study of Spastic Ataxia, Charlevoix-saguenay Type including antibodies and ELISA kits against SACS, ARSACS, SACSIN, APTX, SETX.

Spastic Ataxia, Charlevoix-saguenay Type Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Spastic Ataxia, Charlevoix-saguenay Type below! For more information on how to use Laverne, please read the How to Guide.
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Top Research Reagents

We have 644 products for the study of Spastic Ataxia, Charlevoix-saguenay Type that can be applied to Western Blot, Chromatin Immunoprecipitation, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Chromatin Immunoprecipitation (ChIP), Immunohistochemistry from our catalog of antibodies and ELISA kits.

AF8014
SACS was detected in immersion fixed paraffin-embedded sections of human brain (cerebellum) using Sheep Anti-Human SACS Antigen Affinity-purified Polyclonal Antibody (Catalog # AF8014) at 3 µg/mL overnight at 4 °C. Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # <a class=

Sheep Polyclonal
Species Human
Applications IHC

NBP2-98661
Western Blot: Aprataxin Antibody [NBP2-98661] - Anti-Aprataxin rabbit polyclonal antibody at 1:500 dilution. Lane A: HeLa Whole Cell Lysate. Lane B: A549 Whole Cell Lysate. Lane C: 293 Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size: 40 kDa. Observed band size: 40 kDaImmunocytochemistry/Immunofluorescence: Aprataxin Antibody [NBP2-98661] - Immunofluorescence staining of Aprataxin in PC3 cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human Aprataxin polyclonal antibody (dilution ratio 1:200) at 4C overnight. Then cells were stained with the Alexa Fluor(R)488-conjugated Goat Anti-rabbit IgG Secondary antibody (green). Positive staining was localized to Nucleus.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NBP1-94712
Western Blot: Senataxin Antibody [NBP1-94712] - Input: HeLa whole cell lysate. Beads without antibody IP control. IP: IP from HeLa lysate.Immunocytochemistry/Immunofluorescence: Senataxin Antibody [NBP1-94712] - HeLa cells were fixed for 10 minutes using 10% formalin and then permeabilized for 5 minutes using 1X PBS + 0.5% Triton-X100. The cells were incubated with anti-Senataxin at 2 ug/ml overnight at 4C and detected with an anti-rabbit Dylight 488 (Green) at a 1:500 dilution. Alpha tubulin (DM1A) NB100-690 was used as a co-stain at a 1:1000 dilution and detected with an anti-mouse Dylight 550 (Red) at a 1:500 dilution. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 40X objective.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, Flow, ICC/IF

     1 Review

3 Publications
NBP1-59744
Western Blot: gamma Sarcoglycan Antibody [NBP1-59744] - Lane 1 mouse Heart; 2 mouse Liver (expected negative); 3 mouse Liver; 4 mouse Quadriceps; 5 mouse Triceps; 6 mouse Triceps; 7 mouse Triceps. All lanes 25ug mouse protein. Image from verified customer review.Immunohistochemistry-Frozen: gamma Sarcoglycan Antibody [NBP1-59744] - Mouse tibialis anterior frozen sections. Image from verified customer review.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IHC, IHC-Fr

     2 Reviews

1 Publication
NBP2-67817
Western Blot: HspA4 Antibody (SD0861) [NBP2-67817] - Analysis of HSPA4 on Hela cells lysates using anti-HSPA4 antibody at 1/1,000 dilution.Immunocytochemistry/Immunofluorescence: HspA4 Antibody (SD0861) [NBP2-67817] - Staining HSPA4 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Rabbit Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

NBP1-33633
Western Blot: DNA Polymerase gamma Antibody [NBP1-33633] - Various whole cell extracts (30 ug) were separated by 5% SDS-PAGE, and the membrane was blotted with DNA polymerase gamma antibody  diluted by 1:1000.Immunocytochemistry/Immunofluorescence: DNA Polymerase gamma Antibody [NBP1-33633] - analysis of methanol-fixed HeLa.

Rabbit Polyclonal
Species Human, Rat
Applications WB, ICC/IF, IHC

NBP2-14870
Western Blot: Alpha-TTP Antibody [NBP2-14870] - Mouse tissue extract (50 ug) was separated by 12% SDS-PAGE, and the membrane was blotted with alpha TTP antibody [C2C3], C-term diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.Immunocytochemistry/Immunofluorescence: Alpha-TTP Antibody [NBP2-14870] - Analysis of methanol-fixed MCF-7, using antibody at 1:500 dilution.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

NBP2-01743
Western Blot: Frataxin Antibody (1C12) [NBP2-01743] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY Frataxin (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-Frataxin.Immunocytochemistry/Immunofluorescence: Frataxin Antibody (1C12) [NBP2-01743] Staining of COS7 cells transiently transfected by pCMV6-ENTRY Frataxin.

Mouse Monoclonal
Species Human
Applications WB, Flow, ICC/IF

NBP2-03971
Western Blot: Viperin Antibody [NBP2-03971] - Analysis of viperin using viperin polyclonal antibody. Human brain lysate in the absence (1) and presence (2) of immunizing peptide, mouse brain (3) and rat brain (4) lysate probed with viperin antibody at 3 ug/ml.  Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.Immunohistochemistry-Paraffin: Viperin Antibody [NBP2-03971] - Analysis of viperin using viperin polyclonal antibody. Human rectum tissue probed with viperin antibody at 5 ug/ml.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

NBP1-77685
Western Blot: HSP90 alpha Antibody [NBP1-77685] - Analysis of HSP901a in 1: HeLa. 2: Ntera2. 3: A431. 4: HepG2. 5: MCF7. 6: NIH/3T3. 7: PC12. 8: COS7.Immunocytochemistry/Immunofluorescence: HSP90 alpha Antibody [NBP1-77685] - HSP901a antibody was tested in MCF-7 cells with FITC (green). Nuclei and actin were counterstained with DAPI (blue) and Phalloidin (red).

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ICC/IF

NBP2-93513
Western Blot: PEO1 Antibody [NBP2-93513] - Analysis of extracts of MCF-7 cells, using PEO1.Exposure time: 90s.Immunocytochemistry/Immunofluorescence: PEO1 Antibody [NBP2-93513] - Analysis of A549 cells using PEO1. Blue: DAPI for nuclear staining.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF

NBP1-20939
Western Blot: DHX58 Antibody [NBP1-20939] - Staining of Human Liver lysate (35 ug protein in RIPA buffer). Antibody at 0.3 ug/mL. Primary incubation was 1 hour. Detected by chemiluminescence.Immunohistochemistry-Paraffin: DHX58 Antibody [NBP1-20939] - Negative Control showing staining of paraffin embedded Human Cortex, with no primary antibody.

Goat Polyclonal
Species Human
Applications WB, IHC-P, PEP-ELISA

1 Publication
NBP2-02377
Western Blot: SIL1 Antibody (3E3) [NBP2-02377] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SIL1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SIL1.Immunocytochemistry/Immunofluorescence: SIL1 Antibody (3E3) [NBP2-02377] Staining of COS7 cells transiently transfected by pCMV6-ENTRY SIL1.

Mouse Monoclonal
Species Human
Applications WB, Flow, ICC/IF

H00010049-M01
Western Blot: DNAJB6 Antibody (2C11-C1) [H00010049-M01] - DNAJB6 monoclonal antibody (M01), clone 2C11-C1 Analysis of DNAJB6 expression in Jurkat.Western Blot: DNAJB6 Antibody (2C11-C1) [H00010049-M01] - DNAJB6 monoclonal antibody (M01), clone 2C11-C1. Analysis of DNAJB6 expression in C32.

Mouse Monoclonal
Species Human
Applications ICC/IF (-), WB, ELISA

7 Publications
NB100-56490
Western Blot: ZNF198 Antibody [NB100-56490] - Analysis of ZNF198 in mouse skeletal muscle lysate in the 1) absence and 2) presence of immunizing peptide using this antibody at 0.1 ug/ml.Immunohistochemistry-Paraffin: ZNF198 Antibody [NB100-56490] - Analysis of human breast using this antibody at 10 ug/ml.

Rabbit Polyclonal
Species Human, Canine, Primate
Applications WB, IHC, IHC-P

NBP1-52084
Western Blot: Phenylalanine Hydroxylase Antibody [NBP1-52084] - (0.1ug/ml) staining of Mouse (A) and Rat (B) Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Immunohistochemistry-Paraffin: Phenylalanine Hydroxylase Antibody [NBP1-52084] - Staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

1 Publication
NBP2-02996
Western Blot: DNAJA2 Antibody (3A10) [NBP2-02996] Analysis of extracts (35ug) from 9 different cell lines by using anti-DNAJA2 monoclonal antibody.Immunocytochemistry/Immunofluorescence: DNAJA2 Antibody (3A10) [NBP2-02996] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY DNAJA2.

Mouse Monoclonal
Species Human, Rat, Canine
Applications WB, Flow, ICC/IF


Related Genes

Spastic Ataxia, Charlevoix-saguenay Type has been researched against:

Related PTMs

Spastic Ataxia, Charlevoix-saguenay Type has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Spastic Ataxia, Charlevoix-saguenay Type is also known as Autosomal Recessive Spastic Ataxia Of Charlevoix-saguenay, Charlevoix-saguenay Spastic Ataxia, Spastic Ataxia Of Charlevoix-saguenay.