Submit your image related to Diseases to be featured!

Get Social

Submit your Twitter account related to Pelizaeus-merzbacher Disease to be featured!

Blogs

Submit your blog on Pelizaeus-merzbacher Disease to be featured!

Events

Submit your event on Pelizaeus-merzbacher Disease to be featured!

Videos

Submit your video on Pelizaeus-merzbacher Disease to be featured!

Charities

Submit your charity on Pelizaeus-merzbacher Disease to be featured!

Pelizaeus-merzbacher Disease: Disease Bioinformatics

Research of Pelizaeus-merzbacher Disease has been linked to Diffuse Cerebral Sclerosis Of Schilder, Leukodystrophy, Nervousness, Nystagmus, Paraplegia. The study of Pelizaeus-merzbacher Disease has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Pelizaeus-merzbacher Disease include Myelination, Pathogenesis, Cell Death, Interphase, Reflex. These pathways complement our catalog of research reagents for the study of Pelizaeus-merzbacher Disease including antibodies and ELISA kits against PLP1, PRDX5, PDXP, PTHLH, DM20.

Pelizaeus-merzbacher Disease Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Pelizaeus-merzbacher Disease below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 907 products for the study of Pelizaeus-merzbacher Disease that can be applied to Western Blot, Immunocytochemistry/Immunofluorescence, Flow Cytometry, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NBP1-87781
Immunohistochemistry-Paraffin: Myelin PLP Antibody [NBP1-87781] - Border of a demyelinated lesion. Image from a verified customer review.Immunohistochemistry-Paraffin: Myelin PLP Antibody [NBP1-87781] - Staining of human cerebral cortex shows high expression.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IHC, IHC-P

     1 Review

1 Publication
AF5724
Western blot shows lysates of human, mouse, and rat brain tissue. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human/Mouse/Rat Peroxiredoxin 5 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5724) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=    Peroxiredoxin 5  was detected in immersion fixed A549 human lung carcinoma cell line using  Goat Anti-Human/Mouse/Rat Peroxiredoxin 5 Antigen Affinity-purified  Polyclonal Antibody (Catalog # AF5724) at 10 µg/mL for 3  hours at room temperature. Cells were stained using the  NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody  (red; Catalog # <a class=

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC

NBP2-27461
Western Blot: PDXP Antibody [NBP2-27461] - 0.1 ug/ml staining of Mouse (A) and Rat (B) Brain lysates (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Immunohistochemistry-Paraffin: PDXP Antibody [NBP2-27461] - 5ug/ml staining of paraffin embedded Human Tonsil. Steamed antigen retrieval with citrate buffer Ph 6, AP-staining.

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

1 Publication
NBP1-59322
Western Blot: PTHLH/PTHrP Antibody [NBP1-59322] - HepG2 cell lysate, Antibody Titration: 2.0ug/mlImmunohistochemistry-Paraffin: PTHLH/PTHrP Antibody [NBP1-59322] - Human Lung Alveolar cells (indicated with arrows), 4-8ug/ml.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NBP1-59263
Western Blot: GJC2 Antibody [NBP1-59263] - Antibody Titration: 1 ug/ml Human liver.Immunohistochemistry: GJC2 Antibody [NBP1-59263] - Formalin Fixed Paraffin Embedded Tissue: Human Adult heart Observed Staining: Membrane, some cytoplasm Primary Antibody Concentration: 1:100 Secondary Antibody: Donkey anti-Rabbit-Cy2/3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec Protocol located in Reviews and Data.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NBP2-38445
Western Blot: RNF6 Antibody [NBP2-38445] - Analysis in control (vector only transfected HEK293T lysate) and RNF6 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).Immunocytochemistry/Immunofluorescence: RNF6 Antibody [NBP2-38445] - Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear membrane.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NB600-717
Western Blot: MBP Antibody (12) [NB600-717] - Mouse Brain Tissue lysate probed with Rat anti MBP.Immunocytochemistry/Immunofluorescence: MBP Antibody (12) [NB600-717] - Histological and mRNA analysis of the inflammatory cytokines in the vehicle- or etifoxine-treated mice at onset of clinical symptoms. At day 10 p.i., drug treated animals showed significant differences in MBP staining. Animals treated with etifoxine showed an increase in retention of percentage of MBP coverage (*p = 0.001).  Image collected and cropped by CiteAb from the following publication (http://embomolmed.embopress.org/cgi/doi/10.1002/emmm.201202124), licensed under a CC-BY licence.

Rat Monoclonal
Species Human, Mouse, Rat
Applications WB, ELISA, ICC/IF

     3 Reviews

17 Publications
538-MG


Species Rat

     1 Review

18 Publications
NBP1-86135
Western Blot: Arylsulfatase A/ARSA Antibody [NBP1-86135] - Analysis in human cell line Jurkat.Immunohistochemistry-Paraffin: Arylsulfatase A/ARSA Antibody [NBP1-86135] - Staining of human prostate shows strong granular cytoplasmic positivity in glandular cells.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NBP2-67068
Western Blot: PMP22 Antibody (JM52-30) [NBP2-67068] - Analysis of PMP22 on PC-12 cell using anti-PMP22 antibody at 1/500 dilution.Immunocytochemistry/Immunofluorescence: PMP22 Antibody (JM52-30) [NBP2-67068] - Staining PMP22 in N2A cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Rabbit Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

NBP1-81021
Immunocytochemistry/Immunofluorescence: Myt1 Antibody [NBP1-81021] - Immunofluorescent staining of human cell line SH-SY5Y shows localization to nucleoplasm & cytosol.Immunohistochemistry-Paraffin: Myt1 Antibody [NBP1-81021] - Staining of human cerebellum shows moderate nuclear positivity in cells in granular layer.

Rabbit Polyclonal
Species Human, Mouse
Applications ICC/IF, IHC, IHC-P

3 Publications
NBP2-02275
Western Blot: PKMYT1 Antibody (5E1) [NBP2-02275] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PKMYT1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PKMYT1.Immunocytochemistry/Immunofluorescence: PKMYT1 Antibody (OTI5E1) [NBP2-02275] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY PKMYT1.

Mouse Monoclonal
Species Human
Applications WB, Flow, ICC/IF

NBP2-27206
Western Blot: EMAP-II/AIMP1 Antibody [NBP2-27206] -  Analysis of AIMP1 using AIMP1 antibody. Human HCT116 cell lysate in the 1) absence and 2) presence of immunizing peptide and 3) mouse RAW cell lysate probed with 2 ug/ml of AIMP1 antibody.  Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.Immunohistochemistry-Paraffin: EMAP-II/AIMP1 Antibody [NBP2-27206] -  Staining in human pancreas tissue using AIMP1 antibody at 5 ug/ml.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

1 Publication
AF1034
Western blot shows lysates of mouse liver tissue and mouse spleen tissue. PVDF membrane was probed with 0.25 µg/mL of Goat Anti-Mouse Cathepsin C/DPPI Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1034) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <A class=NoLineLink href=    Western  blot shows lysates of mouse lung tissue and rat lung tissue. PVDF membrane  was probed with 1 µg/mL of Goat Anti-Mouse Cathepsin C/DPPI  Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1034) followed by  HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=

Goat Polyclonal
Species Mouse, Rat
Applications WB, Simple Western, IHC

     1 Review

10 Publications
NBP1-88573
Western Blot: PRG2 Antibody [NBP1-88573] - Analysis in control (vector only transfected HEK293T lysate) and pRG2 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).Immunohistochemistry-Paraffin: PRG2 Antibody [NBP1-88573] - Staining of human skeletal muscle shows no cytoplasmic positivity as expected.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

1 Publication
9086-MB
When Mannan is coated at 0.1 µg/mL (100 µL/well),  Recombinant Human MBL (Catalog # 9086-MB) binds with a typical ED<sub>50</sub> of 25-150 ng/mL.


Species Human

     1 Review

6 Publications
NBP1-77397
Western Blot: HSP60 Antibody [NBP1-77397] - Analysis of extracts from HeLa and COS cells using NBP1-77397 Hsp60 antibody at 1:1000Immunocytochemistry/Immunofluorescence: HSP60 Antibody [NBP1-77397] - Confocal immunofluorescent analysis of HeLa cells using Hsp60 antibody (NBP1-77397, 1:100). An Alexa Fluor 488-conjugated Goat to rabbit IgG was used as secondary antibody (green, A). Actin filaments were labeled with Alexa Fluor 568 phalloidin (red, B). DAPI was used to stain the cell nuclei (blue, C).

Rabbit Polyclonal
Species Human, Mouse
Applications WB, Simple Western, Flow

     4 Reviews

2 Publications
NBP1-30981
Western Blot: ABR Antibody [NBP1-30981] - Sample (30ug whole cell lysate) A:A431, 7.5% SDS PAGE, antibody diluted at 1:1000.Immunocytochemistry/Immunofluorescence: ABR Antibody [NBP1-30981] - Analysis of paraformaldehyde-fixed A431, using  ABR(NBP1-30981) antibody at 1:500 dilution.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF


Related Genes

Pelizaeus-merzbacher Disease has been researched against:

Related PTMs

Pelizaeus-merzbacher Disease has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Pelizaeus-merzbacher Disease is also known as pelizaeus-merzbacher disease, spastic paraplegia 2, hereditary x-linked recessive spastic paraplegia, cockayne-pelizaeus-merzbacher disease, pelizaeus merzbacher brain sclerosis, plp1-related disorders, spg2, pmd, x linked recessive hereditary spastic paraplegia, spastic paraplegia 2, x-linked (disorder), pelizaeus-merzbacher disease (disorder), sclerosis, brain, pelizaeus-merzbacher, anophthalmia and pulmonary hypoplasia, spastic paraplegia type 2, spastic paraplegia-2, spastic paraplegia, leukodystrophies, leukodystrophy, spg 2, sppx2, pmds, hsp2.