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Muscular Dystrophy: Disease Bioinformatics

Muscular dystrophy refers to a group of over 30 progressive muscle weakening disorders that are often disabling. Most forms of muscular dystrophy have symptoms that begin in early childhood, but some have symptoms that do not appear until early to late adulthood. The most common form of muscular dystrophy is Duchenne muscular dystrophy, which affects approximately 1 in 3,500 males. Girls are less affected by the common types of muscular dystrophy, which are inherited in an X-linked manner. There is no cure for any type of muscular dystrophy, and treatment is supportive and often includes use of wheelchairs, walkers, and breathing aids. Many forms of muscular dystrophy have an average life expectancy of late teens to early twenties, but with the introduction of supportive care and more information available about the disorders, the life expectancy is increasing.

Muscular Dystrophy Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Muscular Dystrophy below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 320 products for the study of Muscular Dystrophy that can be applied to Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NB120-7164
Immunohistochemistry-Frozen: Dystrophin Antibody (MANDRA1) [NB120-7164] - Staining of frozen human tongue sections with 1:100 Monoclonal Anti-Dystrophin, Clone: MANDRA1 using Goat Anti-Mouse IgG, FITC-conjugate.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications ELISA, ICC/IF, IHC-Fr

3 Publications
H00007402-M01
Immunocytochemistry/Immunofluorescence: Utrophin Antibody (5G6) [H00007402-M01] - Analysis of monoclonal antibody to UTRN on HeLa cell. Antibody concentration 10 ug/ml.ELISA: Utrophin Antibody (5G6) [H00007402-M01] - Detection limit for recombinant GST tagged UTRN is 0.1 ng/ml as a capture antibody.

Mouse Monoclonal
Species Human
Applications WB, ELISA, ICC/IF

NB120-15109
Western Blot: Dysferlin Antibody [NB120-15109] - Skeletal MuscleImmunohistochemistry-Paraffin: Dysferlin Antibody [NB120-15109] - Human skeletal muscle stained with anti-dysferlin antibody

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NBP2-14868
Western Blot: Alpha Dystroglycan Antibody [NBP2-14868] -  U87-MG whole cell extracts and membrane extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with DAG1 antibody diluted at 1:500.Immunocytochemistry/Immunofluorescence: Alpha Dystroglycan Antibody [NBP2-14868] - HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: alpha Dystroglycan protein stained by alpha Dystroglycan antibody 38) diluted at 1:1000. Red: alpha Tubulin, a cytoskeleton marker, stained by alpha Tubulin antibody [B-5-1-2]  diluted at 1:10000. Blue: Hoechst 33342 staining.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NB300-164
Western Blot: Bestrophin 1 Antibody (E6-6) [NB300-164] - Detection of Bestrophin (68 kDa) from human RPE cell lysate.

Mouse Monoclonal
Species Human, Porcine, Canine
Applications WB, ICC/IF, IHC-Fr

     1 Review

24 Publications
NBP2-25151
Western Blot: Lamin A + C Antibody (4C4) [NBP2-25151] - Stripe blots of crude HeLa cell extract. Note two strong clean bands at 74 kDa and 64 kDa, corresponding to Lamin A and C, in lane 6. Lane 5 was stained with an antibody to Enolase 1. Lanes 3 and 4 were stained with NBP2-25142, the monoclonal antibody to all six Actin isotypes. Molecular weights of each protein are as indicated.Immunocytochemistry/Immunofluorescence: Lamin A + C Antibody (4C4) [NBP2-25151] - HeLa cells staing with NBP2-25151 (red), and counterstained with chicken polyclonal antibody to Vimentin NB300-223 (green) and DNA (blue). NBP2-25151 reveals strong nuclear lamina staining, while the Vimentin antibody reveals cytoplasmic intermediate filaments.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF

H00000825-M01
Immunocytochemistry/Immunofluorescence: Calpain 3 Antibody (1B2) [H00000825-M01] - Analysis of monoclonal antibody to CAPN3 on HeLa cell. Antibody concentration 10 ug/ml.Sandwich ELISA: Calpain 3 Antibody (1B2) [H00000825-M01] - Detection limit for recombinant GST tagged CAPN3 is 0.3 ng/ml as a capture antibody.

Mouse Monoclonal
Species Human
Applications WB, ELISA, ICC/IF

NBP1-85632
Immunocytochemistry/Immunofluorescence: Choline Kinase beta Antibody [NBP1-85632] - Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.Immunohistochemistry-Paraffin: Choline Kinase beta Antibody [NBP1-85632] - Staining of human testis shows cytoplasmic positivity in cells in seminiferous ducts and Leydig cells.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

NBP1-87692
Western Blot: Emerin Antibody [NBP1-87692] - Western blot analysis in mouse cell line NIH-3T3, rat cell line NBT-II and rat cell line pC12.Immunocytochemistry/Immunofluorescence: Emerin Antibody [NBP1-87692] - Immunofluorescent staining of human cell line U-251 MG shows localization to nuclear membrane & endoplasmic reticulum.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

5 Publications
NBP1-85630
Western Blot: Choline kinase alpha Antibody [NBP1-85630] - Analysis in human cell line SK-BR-3.Immunohistochemistry-Paraffin: Choline kinase alpha Antibody [NBP1-85630] - Staining of human testis shows moderate cytoplasmic and nuclear positivity in cells in seminiferous ducts.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NBP1-33383
Western Blot: FKTN Antibody [NBP1-33383] - Sample (30 ug of whole cell lysate) A: H1299 B: Hela 10% SDS PAGE; antibody diluted at 1:1000.Immunocytochemistry/Immunofluorescence: FKTN Antibody [NBP1-33383] - Methanol-fixed HeLa, using FKTN antibody at 1:200 dilution.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF

NBP1-90306
Western Blot: alpha Sarcoglycan Antibody [NBP1-90306] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).Immunohistochemistry-Paraffin: alpha Sarcoglycan Antibody [NBP1-90306] - Staining of human heart muscle shows distinct positivity of intercalated discs in myocytes.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

1 Publication
NB110-5029
Western Blot: Caveolin-3 Antibody [NB110-5029] - Analysis of rat cardiac muscle protein extract.Immunocytochemistry/Immunofluorescence: Caveolin-3 Antibody [NB110-5029] - C2C11 cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with a Caveolin 3 polyclonal antibody at a dilution of 1:20 overnight at 4 C, washed with PBS and incubated with a DyLight-488 conjugated secondary antibody and nuclei with DAPI (blue) is shown.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

1 Publication
NBP2-55584
Immunocytochemistry/Immunofluorescence: FKRP Antibody [NBP2-55584] - Staining of human cell line SH-SY5Y shows localization to nucleus, cytosol & the Golgi apparatus.

Rabbit Polyclonal
Species Human
Applications ICC/IF

MAB6967
Western blot shows lysates of human heart tissue. PVDF membrane was probed with 2 µg/mL of Mouse Anti-Human DMPK Monoclonal Antibody (Catalog # MAB6967) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # <A class=NoLineLink href=

Mouse Monoclonal
Species Human
Applications WB

NBP1-31805
Western Blot: PABPN1 Antibody [NBP1-31805] - Sample (30 ug of whole cell lysate) A: Jurkat 12% SDS PAGE; antibody diluted at 1:1000.Immunocytochemistry/Immunofluorescence: PABPN1 Antibody [NBP1-31805] - A375 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: PABPN1 protein stained by PABPN1 antibody diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 um.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

NBP1-59744
Western Blot: gamma Sarcoglycan Antibody [NBP1-59744] - Lane 1 mouse Heart; 2 mouse Liver (expected negative); 3 mouse Liver; 4 mouse Quadriceps; 5 mouse Triceps; 6 mouse Triceps; 7 mouse Triceps. All lanes 25ug mouse protein. Image from verified customer review.Immunohistochemistry-Frozen: gamma Sarcoglycan Antibody [NBP1-59744] - Mouse tibialis anterior frozen sections. Image from verified customer review.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IHC, IHC-Fr

     2 Reviews


Related Genes

Muscular Dystrophy has been researched against:

Alternate Names

Muscular Dystrophy is also known as Dystrophies, Muscular, Hereditary Progressive Muscular Dystrophy, Muscular Dystrophies, Myodystrophies, Myodystrophy.