Submit your image related to Diseases to be featured!

Get Social

Submit your Twitter account related to Meckel-gruber Syndrome to be featured!

Blogs

Submit your blog on Meckel-gruber Syndrome to be featured!

Events

Submit your event on Meckel-gruber Syndrome to be featured!

Videos

Submit your video on Meckel-gruber Syndrome to be featured!

Charities

Submit your charity on Meckel-gruber Syndrome to be featured!

Meckel-gruber Syndrome: Disease Bioinformatics

Research of Meckel-gruber Syndrome has been linked to Congenital Cerebral Hernia, Polycystic Kidney Diseases, Polydactyly, Dysplasia, Cystic Kidney Diseases. The study of Meckel-gruber Syndrome has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Meckel-gruber Syndrome include Localization, Pathogenesis, Transport, Intraflagellar Transport, Neural Tube Closure. These pathways complement our catalog of research reagents for the study of Meckel-gruber Syndrome including antibodies and ELISA kits against TMEM67, MKS1, MKKS, CEP290, RPGRIP1L.

Meckel-gruber Syndrome Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Meckel-gruber Syndrome below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 683 products for the study of Meckel-gruber Syndrome that can be applied to Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NBP1-06590
Western Blot: Meckelin Antibody [NBP1-06590] - Immunodetection of Meckelin (120kDa) in whole cell extracts of HEK293 cells.Immunohistochemistry-Paraffin: Meckelin Antibody [NBP1-06590] - Staining of kidney tissue section with Meckelin Antibody (NBP1-06590).

Rabbit Polyclonal
Species Human, Rat
Applications WB, ICC/IF, IHC

2 Publications
NBP1-88692
Western Blot: MKS1 Antibody [NBP1-88692] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells), Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells)Immunohistochemistry-Paraffin: MKS1 Antibody [NBP1-88692] - Staining of human colon, fallopian tube, kidney and liver using Anti-MKS1 antibody NBP1-88692 (A) shows similar protein distribution across tissues to independent antibody NBP1-88691 (B).

Rabbit Polyclonal
Species Human, Rat
Applications WB, IHC, IHC-P

NBP1-92123
Western Blot: MKKS Antibody [NBP1-92123] - Lane 1: Marker  [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG spImmunocytochemistry/Immunofluorescence: MKKS Antibody [NBP1-92123] - Immunofluorescent staining of human cell line U-2 OS shows localization to centrosome.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NB100-86991
Western Blot: CEP290 Antibody [NB100-86991] - Detection of human CEP290 by western blot and immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded) and HEK293T (T; 50 ug) cells. Antibodies: Affinity purified rabbit anti-CEP290 antibody NB100-86991 used for WB at 0.1 ug/ml (A) and 1 ug/ml (B) and used for IP at 3 ug/mg lysate. Detection: Chemiluminescence with exposure times of 30 seconds (A) and 10 second (B).Immunocytochemistry/Immunofluorescence: CEP290 Antibody [NB100-86991] - NBF-fixed asynchronous HeLa cells. Antibody used at a dilution of 1:500.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IP

9 Publications
NBP1-84403
Immunohistochemistry-Paraffin: RPGRIP1L Antibody [NBP1-84403] - Staining of human bronchus shows strong cytoplasmic positivity in respiratory epithelial cells.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

2 Publications
MAB1368
Simple Western lane view shows lysates of HepG2 human hepatocellular carcinoma cell line, loaded at 0.2 mg/mL. A specific band was detected for  alpha ‑Fetoprotein/AFP at approximately 70 kDa (as indicated) using 5 µg/mL of Mouse Anti-Human/Mouse  alpha ‑Fetoprotein/AFP Monoclonal Antibody (Catalog # MAB1368). This experiment was conducted under reducing conditions and using the<br>12-230 kDa separation system.    Western  blot shows lysates of HepG2 human hepatocellular carcinoma parental cell line  and  alpha ‑Fetoprotein/AFP knockout HepG2 cell line (KO). PVDF membrane was probed  with 0.1 µg/mL of Mouse Anti-Human/Mouse  alpha ‑Fetoprotein/AFP  Monoclonal Antibody (Catalog # MAB1368) followed by HRP-conjugated Anti-Mouse  IgG Secondary Antibody (Catalog # <a class=

Mouse Monoclonal
Species Human, Mouse
Applications WB, Simple Western, CyTOF-ready

     7 Reviews

45 Publications
NBP2-98647
Western Blot: Nephronophthisis Antibody [NBP2-98647] - Anti-Nephronophthisis rabbit polyclonal antibody at 1:500 dilution. Lane A: Hela Whole Cell Lysate. Lane B: U-251 MG Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size: 80 kDaImmunohistochemistry-Paraffin: Nephronophthisis Antibody [NBP2-98647] - Immunochemical staining of human Nephronophthisis in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NBP1-93673
Immunohistochemistry-Paraffin: CC2D2A Antibody [NBP1-93673] - Staining of human placenta shows strong nuclear and cytoplasmic positivity in trophoblastic cells.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

1 Publication
H00261734-Q01
12.5% SDS-PAGE Stained with Coomassie Blue.


Species Human

H00000583-P01
SDS-Page: Recombinant Human BBS2 Protein [H00000583-P01] - 12.5% SDS-PAGE Stained with Coomassie Blue.


Species Human

464-SH/CF
Recombinant Mouse Sonic Hedgehog/Shh (C25Il), N-Terminus (Catalog # 464-SH/CF) induces alkaline phosphatase production by the C3H10T1/2 mouse embryonic fibroblast cell line. The activity is more than 30-fold greater than the top competitor's Sonic Hedgehog.1 μg/lane of Recombinant Mouse Sonic Hedgehog/Shh (C25Il), N-Terminus was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 22 kDa.


Species Mouse

43 Publications
BC110-60479

Rabbit Polyclonal
Species Human, Mouse
Applications ICC/IF, PEP-ELISA

NBP2-92821
Western Blot: B9D1 Antibody [NBP2-92821] - Analysis of extracts of various cell lines, using B9D1 at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.Immunohistochemistry-Paraffin: B9D1 Antibody [NBP2-92821] - Paraffin-embedded rat kidney using B9D1.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

NBP1-84190
Immunohistochemistry-Paraffin: Nesprin 2 Antibody [NBP1-84190] - Staining of human cerebral cortex, kidney, skin and testis using Anti-SYNE2 antibody NBP1-84190 (A) shows similar protein distribution across tissues to independent antibody NBP2-38620 (B).Immunohistochemistry-Paraffin: Nesprin 2 Antibody [NBP1-84190] - Staining of human testis shows moderate membranous positivity in cells in seminiferous ducts.

Rabbit Polyclonal
Species Human, Rat
Applications WB, IHC, IHC-P

2 Publications
NBP2-47594
Immunocytochemistry/Immunofluorescence: TRIM26 Antibody [NBP2-47594] - Staining  human cell line A-431 shows positivity in cytoplasm and nucleus but excluded from the nucleoli.Immunohistochemistry-Paraffin: TRIM26 Antibody [NBP2-47594] - Staining of human tonsil shows strong cytoplasmic positivity in germinal center and non-germinal center cells.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

NBP1-91693
Western Blot: B9D2 Antibody [NBP1-91693] - Analysis in control (vector only transfected HEK293T lysate) and B9D2 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).Immunohistochemistry-Paraffin: B9D2 Antibody [NBP1-91693] - Staining in human fallopian tube and skeletal muscle tissues using anti-B9D2 antibody. Corresponding B9D2 RNA-seq data are presented for the same tissues.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NBP1-87201
Immunohistochemistry-Paraffin: Prosurfactant Protein C Antibody [NBP1-87201] - Analysis in human lung and kidney tissues using HPA010928 antibody. Corresponding SFTPC RNA-seq data are presented for the same tissues.Western Blot: Prosurfactant Protein C Antibody [NBP1-87201] - Analysis in human lung tissue.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NBP1-87789
Immunocytochemistry/Immunofluorescence: PKC mu Antibody [NBP1-87789] - Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.Immunohistochemistry-Paraffin: PKC mu Antibody [NBP1-87789] - Staining of human parathyroid gland shows cytoplasmic positivity in glandular cells.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

1 Publication
NBP2-15309
Western Blot: AHI1 Antibody [NBP2-15309] - Sample (30 ug of whole cell lysate) A: IMR32 7.5% SDS PAGE; antibody diluted at 1:1000.Immunocytochemistry/Immunofluorescence: AHI1 Antibody [NBP2-15309] - Analysis of methanol-fixed HeLa, using antibody at 1:500 dilution.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC


Related Genes

Meckel-gruber Syndrome has been researched against:

Related PTMs

Meckel-gruber Syndrome has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Meckel-gruber Syndrome is also known as Dysencephalia Splachnocystica, Dysencephalia Splanchnocystica, Gruber Syndrome, Meckel Gruber Syndrome, Meckel Syndrome.