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Lupus Erythematosus, Systemic: Disease Bioinformatics

Lupus Erythematosus, Systemic (commonly known as Lupus) is an autoimmune disease where the body's antibodies attack its own organs, resulting in severe inflammation. Lupus Erythematosus, Systemic affects nearly 10 times as many women as it does men. Individuals are typically diagnosed in their 20s and 30s. Symptoms of Lupus include muscle pain, swelling, fatigue, and a butterfly shaped rash on the face or cheeks. There is no cure for Lupus Erythematosus, Systemic yet treatments focus on alleviating individual symptoms. Medications such as nonsteroidal anti-inflammatory, antimalarial, and immune suppressants are frequently used for individuals with Lupus Erythematosus, Systemic.

Lupus Erythematosus, Systemic Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Lupus Erythematosus, Systemic below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 2305 products for the study of Lupus Erythematosus, Systemic that can be applied to Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NB200-540
Flow (Intracellular): Complement C3 Antibody (11H9) [NB200-540] - An intracellular stain was performed on RAW 246.7 cells with Complement C3 (11H9-3-2) antibody NB200-540 (blue) and a matched isotype control NBP2-31382 (orange). Cells were either treated with 3uM Monensin for 3 hours to block the secretion of Complement C3 (B) or grown in normal media (A). Cells were fixed with 4% PFA and then permeablized with 0.1% saponin. Cells were incubated in an antibody dilution of 2 ug/mL for 30 minutes at room temperature, followed by mouse F(ab)2 IgG (H+L) PE-conjugated secondary antibody (F0102B, R&D Systems).Immunocytochemistry/Immunofluorescence: Complement C3 Antibody (11H9) [NB200-540] - C3 protein fragments deposited on  kidney cells of MPL-lpr mouse. Staining with antibody 11H9. Glomerular staining pattern.

Rat Monoclonal
Species Mouse
Applications WB, Flow, IA

     1 Review

1 Publication
NB600-101
Western Blot: Calreticulin Antibody [NB600-101] - Human kidney lysate.Immunocytochemistry/Immunofluorescence: Calreticulin Antibody [NB600-101] - Immunofluorescence staining of Calreticulin in HCT15 colon cancer cells using NB600-101. Secondary antibody was an Alexa Fluor 488. Photo courtesy of Dr. Birkenkamp Demtroeder, Arhus University Hospital.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, B/N

20 Publications
NBP1-48002
Western Blot: SSB Antibody (2C8) [NBP1-48002] Analysis of extracts (35ug) from 9 different cell lines by using anti-SSB monoclonal antibody.Immunocytochemistry/Immunofluorescence: SSB Antibody (2C8) [NBP1-48002] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY SSB.

Mouse Monoclonal
Species Human, Canine, Primate
Applications WB, ICC/IF, IHC

NBP2-34234
Immunohistochemistry-Paraffin: Complement C4d Antibody (C4D204) [NBP2-34234] - Formalin-fixed, paraffin-embedded human kidney transplant tissue (20X) stained with Complement 4d MAb (C4D204).Immunohistochemistry-Paraffin: Complement C4d Antibody (C4D204) [NBP2-34234] - Formalin-fixed, paraffin-embedded human kidney transplant tissue (10X) stained with Complement 4d MAb (C4D204).

Mouse Monoclonal
Species Human
Applications ICC/IF, IHC-Fr, IHC-P

NBP1-33548
Western Blot: TRIM21/SSA1 Antibody [NBP1-33548] - Sample (30 ug of whole cell lysate) A: Molt-4 10% SDS PAGE; antibody diluted at 1:1000.Immunocytochemistry/Immunofluorescence: TRIM21/SSA1 Antibody [NBP1-33548] - Paraformaldehyde-fixed A431, using antibody at 1:200 dilution.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NBP1-58268
Western Blot: Coagulation Factor II/Thrombin Antibody [NBP1-58268] - 721_B tissue lysate at a concentration of 1ug/ml.Immunohistochemistry: Coagulation Factor II/Thrombin Antibody [NBP1-58268] - Analysis of human liver after heat-induced Antigen retrieval. Antibody concentration 5 ug/ml.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

     1 Review

H00005555-P01
Other Recombinant Human PRH2 Protein


Species Human

NBP1-19371
Western Blot: CD4 Antibody [NBP1-19371] - CD4 antibody was tested in the following cell lysates: Lane 1) human spleen 2) human tonsil 3) human placenta 4) human kidney 5) human liver 6) mouse spleen 7) mouse placenta 8) rat placenta.Immunocytochemistry/Immunofluorescence: CD4 Antibody [NBP1-19371] - CD4 antibody was tested in Jurkat cells with Dylight 488 (green). Nuclei were counterstained with DAPI (blue).

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ICC/IF

     6 Reviews

12 Publications
NBP1-84550
Western Blot: HLA DQA1 Antibody [NBP1-84550] - Lane 1: Marker  [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10.  Lane 2: Human cell line Daudi.Immunocytochemistry/Immunofluorescence: HLA DQA1 Antibody [NBP1-84550] - Staining of human cell line U-251MG shows positivity in cytoplasm.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NB100-524
Western Blot: NOD2 Antibody (2D9) [NB100-524] - Total protein from human THP1 and US-OS cells and mouse Raw264.7 cells was separated on a 7.5% gel by SDS-PAGE, transferred to PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 2.0 ug/ml anti-NOD2 in 1% non-fat milk in TBST and detected with an anti-mouse HRP secondary antibody using chemiluminescence.Immunocytochemistry/Immunofluorescence: NOD2 Antibody (2D9) [NB100-524] - A431 cells were fixed for 10 minutes using 10% formalin and then permeabilized for 5 minutes using 1X TBS + 0.5% Triton-X100. The cells were incubated with anti-NOD2 (2D9) NB100-524 at a 1:200 dilution overnight at 4C and detected with an anti-mouse Dylight 488 (Green) at a 1:500 dilution. Actin was counterstained with Phalloidin 568 (Red) at a 1:200 dilution. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 40X objective.

Mouse Monoclonal
Species Human, Mouse
Applications WB, Flow, ICC/IF

     1 Review

13 Publications
NB600-41532
Western Blot: Albumin Antibody [NB600-41532] - Analysis using the HRP conjugate of NB600-41532. Detection of Albumin in whole mouse liver extracts. Image courtesy of anonymous customer product review.

Goat Polyclonal
Species Mouse
Applications WB, ELISA, ICC/IF

38 Publications

Related Genes

Lupus Erythematosus, Systemic has been researched against:

Alternate Names

Lupus Erythematosus, Systemic is also known as Disseminated Lupus Erythematosus, Le Syndrome, Lupus, Lupus Erythematosus, Lupus Erythematosus Disseminatus.