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Fragile X Syndrome: Disease Bioinformatics

Research of Fragile X Syndrome has been linked to Sex Chromosome Aberrations, Autistic Disorder, Trinucleotide Repeat Expansion, Ataxia, Down Syndrome. The study of Fragile X Syndrome has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Fragile X Syndrome include Methylation, Translation, Pathogenesis, Cognition, Localization. These pathways complement our catalog of research reagents for the study of Fragile X Syndrome including antibodies and ELISA kits against FMR-1, MGLUR, AR, BDNF, CA1.

Fragile X Syndrome Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Fragile X Syndrome below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 692 products for the study of Fragile X Syndrome that can be applied to Western Blot, Chromatin Immunoprecipitation, Immunocytochemistry/Immunofluorescence, Flow Cytometry, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NBP2-01770
Western Blot: FMRP Antibody (1C6) [NBP2-01770] Analysis of extracts (35ug) from 9 different cell lines by using anti-FMRP monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).Immunocytochemistry/Immunofluorescence: FMRP Antibody (1C6) [NBP2-01770] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY FMRP.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

     1 Review

NBP2-13195
Western Blot: RABEP2 Antibody [NBP2-13195] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Human cell line RT-4Immunocytochemistry/Immunofluorescence: RABEP2 Antibody [NBP2-13195] - Immunofluorescent staining of human cell line MCF7 shows localization to cytosol & vesicles.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NBP1-47757
Western Blot: FRA-1/FOSL1 Antibody (12F9) [NBP1-47757] -  HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FOSL1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FOSL1.Immunohistochemistry-Paraffin: FRA-1/FOSL1 Antibody (12F9) [NBP1-47757] -  Carcinoma of bladder tissue.

Mouse Monoclonal
Species Human
Applications WB, IHC, IHC-P

NBP2-55795
Immunocytochemistry/Immunofluorescence: NUFIP2 Antibody [NBP2-55795] - Staining of human cell line CACO-2 shows localization to nucleoplasm & cytosol.

Rabbit Polyclonal
Species Human
Applications ICC/IF

NBP1-81872
Immunohistochemistry-Paraffin: AFF2 Antibody [NBP1-81872] - Staining of human hippocampus shows cytoplasmic positivity in neuronal cells.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

MAB4514
MG‑63 human osteosarcoma cell line was stained with Mouse Anti-Human mGluR5 Monoclonal Antibody (Catalog # MAB4514, filled histogram) or isotype control antibody (Catalog # <a class=NoLineLink href='http://www.rndsystems.com/search?keywords=MAB002'>MAB002</a>, open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG F(ab')<sub>2</sub> Secondary Antibody (Catalog # <a class=NoLineLink href=

Mouse Monoclonal
Species Human
Applications WB, CyTOF-ready, ICFlow

     1 Review

NBP1-89546
Western Blot: FXR1 Antibody [NBP1-89546] - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II.Immunocytochemistry/Immunofluorescence: FXR1 Antibody [NBP1-89546] - Immunofluorescent staining of human cell line A-431 shows localization to cytosol.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ICC/IF

1 Publication
NB300-259
Western Blot: FXR2 Antibody (1G2) [NB300-259] - Whole cell HeLa lysate at a concentration of 1:2500 (lane 1) and 1:500 (lane 2).Immunocytochemistry/Immunofluorescence: FXR2 Antibody (1G2) [NB300-259] - FXR2 (1G2) antibody was tested in HeLa cells with DyLight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red).

Mouse Monoclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

1 Publication
NBP1-33581
Immunocytochemistry/Immunofluorescence: Factor IX Antibody [NBP1-33581] - HepG2 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Factor IX protein stained by Factor IX antibody [N3C3] diluted at 1:500. Blue: Hoechst 33342 staining.Immunohistochemistry-Paraffin: Factor IX Antibody [NBP1-33581] - Paraffin-embedded rat liver. Factor IX antibody [N3C3]  diluted at 1:500.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications ICC/IF, IHC, IHC-P

NB100-56326
Western Blot: MeCP2 Antibody [NB100-56326] - analysis of MeCP2 in HeLa cell lysate using this antibody.Immunocytochemistry/Immunofluorescence: MeCP2 Antibody [NB100-56326] - MeCP2 antibody was tested in A431 cells at a 1:200 dilution against Dylight 488 (Green). Alpha tubulin and nuclei were counterstained against Dylight 568 (Red) and DAPI (Blue), respectively.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

1 Publication
NB100-56603
Western Blot: Androgen R/NR3C4 [p Ser213, p Ser210] Antibody (156C135.2) [NB100-56603] - Analysis using Azide Free version of NB100-56603. LNCaP cells (passage number 38) were serum-starved for 2 days. After serum starvation, cells were (A) left untreated, (B) treated with 100 ng/ml IGF-1 for 4h, or (C) incubated with 20 um LY294002 for 30 mi

Mouse Monoclonal
Species Human, Primate
Applications WB, IHC, IHC-P

12 Publications
NB600-607
Western Blot: TOR/mTOR [p Ser2448] Antibody [NB600-607] - Detection of a 250 kDa band (indicated) corresponding to phosphorylated human mTOR present in a 293T whole cell lysates. Cells were serum-starved for 24 hours prior to harvest. 20 ug of lysate was loaded per lane for SDS-PAGE. Untreated cells are shown in lane 1, whereas cells in lane 2 were treated with IGF-1 (100 ng/ml) for 20 min prior to harvest. Follow reaction of antibody with a 1:2000 dilution of HRP Goat-a-Rabbit IgG for visualization.Immunohistochemistry: TOR/mTOR [p Ser2448] Antibody [NB600-607] - Used at 5 ug/ml to detect signal in a variety of tissues including multi-human, multi-brain and multi-cancer slides. This image shows moderate staining of proximal convoluted tubules of the kidney. Tissue was formalin-fixed and paraffin embedded. The image shows localization of the antibody as the precipitated red signal, with a hematoxylin purple nuclear counterstain.

Rabbit Polyclonal
Species Human, Rat
Applications WB, ELISA, IHC

5 Publications
NBP1-42827
Western Blot: MAP1B [p Thr1265] Antibody (SuperBUGS) [NBP1-42827] - Analysis of phosphorylated MAP1B in chick embryos (lane 1) and rat neonatal brain (lane 2).Immunohistochemistry: MAP1B [p Thr1265] Antibody (SuperBUGS) [NBP1-42827] - Immunohistochemical analysis of rat spinal cord transverse section from an E12 embryo.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

8 Publications
NBP2-04611
Western Blot: PRB1 Overexpression Lysate (Adult Normal) [NBP2-04611] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PRB1.


Species Human

NBP1-88191
Western Blot: Carbonic Anhydrase I/CA1 Antibody [NBP1-88191] - Analysis in human cell line HELA.Immunohistochemistry-Paraffin: Carbonic Anhydrase I/CA1 Antibody [NBP1-88191] - Staining in human rectum and pancreas tissues using anti-CA1 antibody. Corresponding CA1 RNA-seq data are presented for the same tissues.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NB100-236
Western Blot: Glucose 6 Phosphate Dehydrogenase Antibody [NB100-236] - Detection of Human and Mouse G6PD by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa, 293T, and mouse NIH3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-G6PD antibody NB100-236 used for WB at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.Western Blot: Glucose 6 Phosphate Dehydrogenase Antibody [NB100-236] - Detection of Human and Mouse G6PD by Western Blot and Immunoprecipitation.  Samples: Whole cell lysate (15 or 25 mcg for human; 20 mcg for mouse WB; 1 mg for mouse IP/WB) from human umbilical vein endothelial cells or mouse peritoneal macrophages from wildtype or G6PD deficient mice.  Antibody:  Affinity purified rabbit anti-G6PD used at 0.6 mcg/ml (A) and 0.5 mcg/ml (B) for WB or 3.75 mcg/mg lysate for IP (B).  Detection: Chemiluminescence.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IB, IHC-Fr

17 Publications
248-BD
1 μg/lane of Recombinant Human BDNF was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 13 kDa.Recombinant Human BDNF (Catalog #<br>248‑BD) stimulates cell proliferation in the BaF mouse pro-B cell line transfected with TrkB. The ED<sub>50</sub> for this effect is 0.2-2 ng/mL.


Species Human, Mouse, Rat

     6 Reviews

98 Publications

Related Genes

Fragile X Syndrome has been researched against:

Related PTMs

Fragile X Syndrome has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Fragile X Syndrome is also known as fragile x syndrome, fraxa syndrome, martin-bell syndrome, fragile x mental retardation syndrome, x-linked mental retardation and macro-orchidism, mental retardation, x-linked.