Submit your image related to Diseases to be featured!

Get Social

Submit your Twitter account related to Epilepsy to be featured!

Blogs

Submit your blog on Epilepsy to be featured!

Events

Submit your event on Epilepsy to be featured!

Videos

Submit your video on Epilepsy to be featured!

Charities

Submit your charity on Epilepsy to be featured!

Epilepsy: Disease Bioinformatics

Epilepsy is defined as a diverse set of neurological disorders characterized by seizures. These seizures occur due to abnormal electrical activity in the brain. Factors that may lead to epilepsy include, but are not limited to, brain trauma, gene mutations, strokes, brain cancer, and extensive drug and alcohol use. Seizures occur due to a large release of glutamate, which causes a spread of excitation throughout the brain, which propagates the electrical signal and can lead to neuronal death. About 50 million people have epilepsy, with 80% of that population located in developing countries. It is possible to control epilepsy with medicine, but many cases may require surgery in order to relieve symptoms.

Epilepsy Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Epilepsy below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 928 products for the study of Epilepsy that can be applied to Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

AF2180
    Western  blot shows lysates of HEL 92.1.7 human erythroleukemic cell line,  human liver tissue, and human colon tissue. PVDF membrane was probed with  0.1 µg/mL of Goat Anti-Human Carbonic Anhydrase I/CA1  Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2180) followed by  HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=    Simple  Western lane view shows lysates of HEL 92.1.7 human erythroleukemic  cell line and human liver tissue, loaded at 0.2 mg/mL. A specific  band was detected for Carbonic Anhydrase I/CA1 at approximately  38 kDa (as indicated) using 5 µg/mL of Goat Anti-Human  Carbonic Anhydrase I/CA1 Antigen Affinity-purified Polyclonal  Antibody (Catalog # AF2180) followed by 1:50 dilution of HRP-conjugated  Anti-Goat IgG Secondary Antibody (Catalog # <a class=

Goat Polyclonal
Species Human
Applications WB, Simple Western, IP

AF2185
    Western  blot shows lysates of human, mouse, and rat skeletal muscle tissue and heart tissue. PVDF  membrane was probed with 0.1 µg/mL of Goat Anti-Human/Mouse/<br>Rat Carbonic  Anhydrase III/CA3 Antigen Affinity-purified Polyclonal Antibody  (Catalog # AF2185) followed by HRP-conjugated Anti-Goat IgG Secondary  Antibody (Catalog # <a class=

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, IP

1 Publication
NBP2-42388
Western Blot: LAMC2 Antibody (CL2980) [NBP2-42388] - Analysis in human cell line A-431.Immunohistochemistry-Paraffin: LAMC2 Antibody (CL2980) [NBP2-42388] - Staining of human lymph node shows absence of immunoreactivity in lymphoid tissue (negative control).

Mouse Monoclonal
Species Human
Applications WB, IHC, IHC-P

NB100-1533
Western Blot: POMC Antibody [NB100-1533] - Western blot analysis of POMC using NB100-1533 at 0.01ug/ml in NIH 3T3 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Immunohistochemistry-Paraffin: POMC Antibody [NB100-1533] - Analysis in human Anterior Pituitary Gland shows vesilulate staining in glandular cells.

Goat Polyclonal
Species Human, Mouse, Porcine
Applications WB, ICC/IF, IHC

6 Publications
NBP2-58876
Immunocytochemistry/Immunofluorescence: Scn1a Antibody [NBP2-58876] - Staining of human cell line ASC TERT1 shows localization to nucleoplasm & plasma membrane.

Rabbit Polyclonal
Species Human
Applications ICC/IF

NBP1-51843
Western Blot: Aurora A Antibody [NBP1-51843] - WB detection of Aurora A in HeLa whole cell lysate.Immunocytochemistry/Immunofluorescence: Aurora A Antibody [NBP1-51843] - IF Confocal analysis of HeLa cells using Aurora A antibody (NBP1-51843, 1:10). An Alexa Fluor 488-conjugated Goat to rabbit IgG was used as secondary antibody (green). Actin filaments were labeled with Alexa Fluor 568 phalloidin (red). DAPI was used to stain the cell nuclei (blue).

Rabbit Polyclonal
Species Human, Mouse
Applications WB, Simple Western, ICC/IF

     1 Review

4 Publications
NBP2-24916
Western Blot: Catalase Antibody [NBP2-24916] - Analysis in liver lysate of 1) human 2) mouse and 3) rat at 0.1 ug/ml.Immunohistochemistry-Paraffin: Catalase Antibody [NBP2-24916] - Staining of human liver tissue using an isotype control (top) and this antibody (bottom) at 5 ug/ml.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

     1 Review

4 Publications
NB110-41404
Western Blot: Glutamine Synthetase Antibody [NB110-41404] - Analysis of glutamine synthase. 40ug of lysates from mouse (Lanes M), rat (Lanes R), pig (Lanes P), bovine (Lanes B), or human (Lanes Hu) retina were probed. A 42 kDa band was identified in lysates from retinas of all species.Immunohistochemistry: Glutamine Synthetase Antibody [NB110-41404] - Localization of glutamine synthase in the retina. Paraffin sections of mouse (A, B), rat (C, D, G-I), or human (E, F) retina fixed in 4% paraformaldehyde were reacted with anti-glutamine synthase (red fluorescence staining in B, D, G, I, and brown immuno-peroxidase reaction [using ABC kit and visualization with DAB product in F]. Nuclei in some immunofluorescence experiments (A-D) were stained with DAPI (shown in cyan), and with nuclear fast red in E and F.  On inspection at low magnification, anti- glutamine synthase reacted with a single population of cells extending from the ganglion cell layer (GCL) through the inner nuclear layer (INL). No signal was detected in controls either pre-incubated with 100ug/ml of the immunizing peptide (A) or with pre-immune serum (C, E). The pattern of staining observed in all experiments is typicals. This finding was confirmed by co-localization (indicated by yellow in I) of glutamine synthase (red in G) with antoher marker of glutamine synthase (green in H).

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC

     1 Review

1 Publication
NBP2-32001
Immunohistochemistry-Paraffin: SQLE Antibody [NBP2-32001] - Staining of human testis shows strong cytoplasmic positivity in Leydig cells.

Rabbit Polyclonal
Species Human, Mouse
Applications IHC, IHC-P

1 Publication
NB300-141
Immunocytochemistry/Immunofluorescence: GFAP Antibody [NB300-141] - ICC-IF analysis of mixed neuron-glial cultures using GFAP antibody NB300-141 (red) and Vimentin antibody NB300-223 (green). The fibroblastic cells contain only Vimentin and so are green.  The astrocytes contain either Vimentin and GFAP (appearing golden) or predominantly GFAP (appearing red). Blue is nuclear DNA stain.Immunocytochemistry/Immunofluorescence: GFAP Antibody [NB300-141] - Rat neurons stained with Neurofilament Heavy antibody NB300-217 (red) and GFAP antibody NB300-141 (green).

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ICC/IF

     4 Reviews

32 Publications
NBP2-45897
Western Blot: GLYAT Antibody (4D1) [NBP2-45897] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GLYAT.Immunohistochemistry: GLYAT Antibody (4D1) [NBP2-45897] - Analysis of Carcinoma of Human liver tissue.(Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120C for 3 min)

Mouse Monoclonal
Species Human
Applications WB, IHC

NBP1-86616
Western Blot: CRAT Antibody [NBP1-86616] - Lane 1: Marker  [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG spImmunohistochemistry-Paraffin: CRAT Antibody [NBP1-86616] - Staining of human testis shows strong cytoplasmic positivity in cells in seminiferous ducts.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NBP1-46535

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-Fr

6 Publications
AF1107

Goat Polyclonal
Species Mouse
Applications WB, IHC

2 Publications
H00003347-M01
Immunocytochemistry/Immunofluorescence: Histatin 3 Antibody (4G9) [H00003347-M01] - Analysis of monoclonal antibody to HTN3 on HeLa cell. Antibody concentration 10 ug/ml.Sandwich ELISA: Histatin 3 Antibody (4G9) [H00003347-M01] - Detection limit for recombinant GST tagged HTN3 is approximately 3ng/ml as a capture antibody.

Mouse Monoclonal
Species Human
Applications ELISA, ICC/IF