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Dihydropyrimidine Dehydrogenase Deficiency: Disease Bioinformatics

Research of Dihydropyrimidine Dehydrogenase Deficiency has been linked to Malignant Neoplasms, Neoplasms, Colorectal Neoplasms, Neurotoxicity Syndromes, Colorectal Cancer. The study of Dihydropyrimidine Dehydrogenase Deficiency has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Dihydropyrimidine Dehydrogenase Deficiency include Excretion, Methylation, Transport, Pathogenesis, Response To 5-fluorouracil. These pathways complement our catalog of research reagents for the study of Dihydropyrimidine Dehydrogenase Deficiency including antibodies and ELISA kits against ADSL, APRT, BRCA2, CACNA1C, DPYD.

Dihydropyrimidine Dehydrogenase Deficiency Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Dihydropyrimidine Dehydrogenase Deficiency below! For more information on how to use Laverne, please read the How to Guide.
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Top Research Reagents

We have 1246 products for the study of Dihydropyrimidine Dehydrogenase Deficiency that can be applied to Western Blot, Chromatin Immunoprecipitation, Immunocytochemistry/Immunofluorescence, Flow Cytometry, Immunohistochemistry from our catalog of antibodies and ELISA kits.

H00001806-M01
Western Blot: DPYD Antibody (7D4) [H00001806-M01] - DPYD monoclonal antibody (M01), clone 7D4 Analysis of DPYD expression in HeLa.Immunocytochemistry/Immunofluorescence: DPYD Antibody (7D4) [H00001806-M01] - Analysis of monoclonal antibody to DPYD on HeLa cell. Antibody concentration 10 ug/ml.

Mouse Monoclonal
Species Human
Applications WB, ELISA, ICC/IF

1 Publication
NBP1-85224
Western Blot: DPYS Antibody [NBP1-85224] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10 Lane 2: Negative control (vector only transfected HEK293T lysate) Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY419991)Immunohistochemistry-Paraffin: DPYS Antibody [NBP1-85224] -  Staining of human pancreas shows low expression as expected.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NB600-1342

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Func, IA

6 Publications
NBP2-37384
Western Blot: Integrin alpha 2b/CD41 Antibody (2E10C9) [NBP2-37384] - Western blot analysis using ITGA2B mAb against HEK293 (1) and ITGA2B (AA: 45-149)-hIgGFc transfected HEK293 (2) cell lysate.Immunohistochemistry: Integrin alpha 2b/CD41 Antibody (2E10C9) [NBP2-37384] - Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using ITGA2B mouse mAb with DAB staining.

Mouse Monoclonal
Species Human
Applications WB, ELISA, Flow

NBP2-35006
SDS-Page: Human FABP6 Protein [NBP2-35006]


Species Human

NBP1-83411
Immunocytochemistry/Immunofluorescence: STK36 Antibody [NBP1-83411] - Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol.Immunohistochemistry-Paraffin: STK36 Antibody [NBP1-83411] - Staining of human testis shows strong cytoplasmic positivity in cells in seminiferous ducts.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

NBP2-34390

Mouse Monoclonal
Species Human
Applications WB, Flow, ICC/IF

     1 Review

NBP2-16558
Western Blot: G protein alpha inhibitor 1 Antibody [NBP2-16558] - Sample (30 ug of whole cell lysate) A: JurKat 10% SDS PAGE gel, diluted at 1:1000.Immunohistochemistry-Paraffin: G protein alpha inhibitor 1 Antibody [NBP2-16558] - Immunohistochemical analysis of paraffin-embedded Breast ca, using antibody at 1:250 dilution.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NBP2-03107
Western Blot: Adenylosuccinate Lyase Antibody (2D10) [NBP2-03107] Analysis of extracts (35ug) from 9 different cell lines by using anti-Adenylosuccinate Lyase monoclonal antibody.Immunohistochemistry-Paraffin: Adenylosuccinate Lyase Antibody (2D10) [NBP2-03107] - Staining of paraffin-embedded Human lymphoma tissue using anti-Adenylosuccinate Lyase mouse monoclonal antibody.

Mouse Monoclonal
Species Human, Rat, Canine
Applications WB, Flow, IHC

H00051733-M09
Western Blot: beta ureidopropionase Antibody (3F12) [H00051733-M09] - Analysis of UPB1 expression in human liver.Immunohistochemistry-Paraffin: beta ureidopropionase Antibody (3F12) [H00051733-M09] - Analysis of monoclonal antibody to UPB1 on formalin-fixed paraffin-embedded human placenta. Antibody concentration 3 ug/ml

Mouse Monoclonal
Species Human
Applications WB, ELISA, IHC

AF231
    Western  blot shows lysates of HeLa human cervical epithelial carcinoma cell line and  MDA‑MB‑231 human breast cancer cell line. PVDF membrane  was probed with 1 µg/mL of Goat Anti-Human EGFR  Antigen Affinity-purified Polyclonal Antibody (Catalog # AF231) followed by  HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=    A431  human epithelial carcinoma cell line was stained with Goat Anti-Human  EGFR Antigen Affinity-purified Polyclonal Antibody (Catalog #  AF231, filled histogram) or isotype control antibody (Catalog # <a class=

Goat Polyclonal
Species Human
Applications WB, Flow, IHC

6 Publications
NBP1-89519
Western Blot: APRT Antibody [NBP1-89519] - Lane 1: Marker  [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.  Lane 2: Human cell line RT-41Immunocytochemistry/Immunofluorescence: APRT Antibody [NBP1-89519] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

AF6490
Western blot shows lysates of human liver tissue. PVDF Membrane was probed with 1 µg/mL of Goat Anti-Human Glucuronosyltransferase 1A1/UGT1A1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6490) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <A class=NoLineLink href=Glucuronosyltransferase 1A1/UGT1A1 was detected in immersion fixed paraffin-embedded sections of human liver using Goat Anti-Human Glucuronosyltransferase  1A1/<BR>UGT1A1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6490) at 3 µg/mL overnight at 4 °C. Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent‑Basic (Catalog # <A class=NoLineLink href=

Goat Polyclonal
Species Human
Applications WB, IHC, ICC

NBP2-02710
Western Blot: Thromboxane synthase Antibody (2C1) [NBP2-02710] Analysis of extracts (35ug) from 9 different cell lines by using anti-Thromboxane synthase monoclonal antibody.Immunocytochemistry/Immunofluorescence: Thromboxane synthase Antibody (2C1) [NBP2-02710] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY Thromboxane synthase.

Mouse Monoclonal
Species Human, Rat
Applications WB, Flow, ICC/IF

MAB2476
Western blot shows lysates of Capan‑1 human pancreatic adenocarcinoma cell line, HeLa human cervical epithelial carcinoma cell line, and U2OS human osteosarcoma cell line. PVDF membrane was probed with 0.2 µg/mL of Human BRCA2 Monoclonal Antibody (Catalog # MAB2476) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # <a class=

Mouse Monoclonal
Species Human
Applications WB, IHC

5 Publications
NBP2-37607
Western Blot: MTHFR Antibody (5D3) [NBP2-37607] - Western blot analysis using MTHFR mouse mAb against Rat Heart cell lysate.Immunohistochemistry: MTHFR Antibody (5D3) [NBP2-37607] - Immunohistochemical analysis of paraffin-embedded lung cancer using MTHFR mouse mAb with DAB staining.

Mouse Monoclonal
Species Human, Rat
Applications WB, ELISA, IHC

NB100-56561
Western Blot: MITF Antibody (21D1418) [NB100-56561] - Analysis of A375 lysate using MITF antibody at 4 ug/ml.Western Blot: MITF Antibody (21D1418) [NB100-56561] - Western blot analysis of HeLa lysate (35ug per lane, RIPA buffer) using MiTF antibody (NB100-56561) at 0.1ug/ml. Band detected at ~60kDa. (Expected MW of 58.2kDa according to NP_937802.1).

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB

1 Publication
NB100-182
Immunocytochemistry/Immunofluorescence: FANCD2 Antibody [NB100-182] - Analysis using the Biotin conjugate of NB100-182. FancD2 colocalizes in vivo with another protein in SiHa cells after cell exposure to IR. Proliferating SiHa cells were exposed to 10 Gy of IR and double color immunofluorescence staining was performed after 8 h. Images were captured in a Kodak digital image system on a Leica fluorescence microscope.Western Blot: FANCD2 Antibody [NB100-182] - Analysis of FANCD2 in human PD20 cells. Image courtesy of anonymous customer review

Rabbit Polyclonal
Species Human, Mouse, Canine
Applications WB, Simple Western, Flow

     6 Reviews

130 Publications
NBP2-45397
Western Blot: PD-ECGF/Thymidine Phosphorylase Antibody (7A6) [NBP2-45397] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PD-ECGF/Thymidine Phosphorylase.Immunohistochemistry: PD-ECGF/Thymidine Phosphorylase Antibody (7A6) [NBP2-45397] - Analysis of Carcinoma of Human lung tissue.(Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)

Mouse Monoclonal
Species Human
Applications WB, IHC, IHC-P

NBP1-22439
Western Blot: Cav1.2 Antibody (S57-46) [NBP1-22439] - analysis of Hamster T-CHO cell lysate showing detection of CaV1.2 Calcium Channel protein using Mouse Anti-CaV1.2 Calcium Channel Monoclonal Antibody, Clone S57-46. Primary Antibody: Mouse Anti-CaV1.2 Calcium Channel Monoclonal Antibody at 1:1000.Immunohistochemistry-Paraffin: Cav1.2 Antibody (S57-46) [NBP1-22439] - Tissue: Brain Tissue. Species: Mouse. Fixation: Formalin. Primary Antibody: Mouse Anti-CaV1.2 Calcium channel Monoclonal Antibody at 1:10000 for 12 hours at 4C. Secondary Antibody: Biotin Goat Anti-Mouse at 1:2000 for 1 hour at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 200 ul for 2 minutes at RT. Magnification: 40x.

Mouse Monoclonal
Species Human, Mouse, Rabbit
Applications WB, ICC/IF, IHC

1 Publication

Related Genes

Dihydropyrimidine Dehydrogenase Deficiency has been researched against:

Related Pathways

Dihydropyrimidine Dehydrogenase Deficiency has been linked to:

Related PTMs

Dihydropyrimidine Dehydrogenase Deficiency has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Dihydropyrimidine Dehydrogenase Deficiency is also known as dihydropyrimidine dehydrogenase deficiency, hereditary thymine-uraciluria, dpd deficiency, dihydropyrimidine dehydrogenase deficiency (disorder), dihydrouracil dehydrogenase (nadp^+^) deficiency, dihydrouracil dehydrogenase deficiency, dihydropyrimidinase deficiency, familial pyrimidinaemia, dihydropyrimidinuria, familial pyrimidemia, thymine-uracilurea.