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Diabetes Mellitus: Disease Bioinformatics

Diabetes Mellitus, more commonly known as diabetes, is a condition in which blood sugar levels are abnormally high. Usually, the body breaks down the food you eat into glucose, which is used as energy in the body. Cells in the body need insulin, which is a hormone in the bloodstream, to take in the glucose and use it as energy. A person with diabetes is either unable to produce enough insulin or is unable to use the insulin it produces. Because a person with diabetes isn’t able to take in glucose, it builds up in the blood stream which can cause further complications, such as heart disease and kidney disease.

Diabetes Mellitus Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Diabetes Mellitus below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 2531 products for the study of Diabetes Mellitus that can be applied to Chromatin Immunoprecipitation, Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence from our catalog of antibodies and ELISA kits.

NBP2-34260
Immunohistochemistry-Paraffin: Insulin Antibody (E2-E3 (same as INS04)) [NBP2-34260] - Formalin-fixed, paraffin-embedded human pancreas stained with insulin Monoclonal Antibody (E2-E3)SDS-Page: Insulin Antibody (E2-E3 (same as INS04)) [NBP2-34260]

Mouse Monoclonal
Species Human, Mouse, Porcine
Applications WB, Flow, ICC/IF

     4 Reviews

NB600-41532
Western Blot: Albumin Antibody [NB600-41532] - Analysis using the HRP conjugate of NB600-41532. Detection of Albumin in whole mouse liver extracts. Image courtesy of anonymous customer product review.

Goat Polyclonal
Species Mouse
Applications WB, ELISA, ICC/IF

39 Publications
210-TA
Recombinant Human TNF-alpha  (Catalog # 210‑TA) induces cytotoxicity in the L-929 mouse fibroblast cell line in the presence of the metabolic inhibitor actinomycin D. The ED<sub>50</sub> for this effect is 25‑100 pg/mL.1 µg/lane of Recombinant Human TNF-alpha  was resolved by SDS-PAGE with silver staining, under reducing (R) conditions, showing a band at 17 kDa.


Species Human

     21 Reviews

527 Publications
AF1513
    Western  blot shows lysates of mouse lung tissue. PVDF membrane was probed with  0.05 µg/mL of Goat Anti-Mouse ACE/CD143 Antigen Affinity-purified  Polyclonal Antibody (Catalog # AF1513) followed by HRP-conjugated Anti-Goat  IgG Secondary Antibody (Catalog # <a class=    Simple  Western lane view shows lysates of mouse lung tissue, loaded at  0.2 mg/mL. A specific band was detected for ACE/CD143 at  approximately 218 kDa (as indicated) using 10 µg/mL of Goat  Anti-Mouse ACE/CD143 Antigen Affinity-purified Polyclonal Antibody (Catalog #  AF1513) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary  Antibody (Catalog # <a class=

Goat Polyclonal
Species Mouse
Applications WB, Simple Western, Flow

     1 Review

3 Publications
MAB1249
     beta TC‑6  mouse beta cell insulinoma cell line was stained with Mouse Anti-Human/Mouse  Glucagon Monoclonal Antibody (Catalog # MAB1249, filled histogram) or isotype  control antibody (Catalog # <a class=Glucagon was detected in immersion fixed beta TC-6 mouse beta cell insulinoma cell line using 10 µg/mL Human/Mouse Glucagon Monoclonal Antibody (Catalog # MAB1249) for 3 hours at room temperature. Cells were stained with the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # <A class=

Mouse Monoclonal
Species Human, Mouse
Applications CyTOF-ready, ICC, ICFlow

     3 Reviews

4 Publications
NBP1-69565
Western Blot: ST3GAL4 Antibody [NBP1-69565] - This Anti-ST3GAL4 antibody was used in Western Blot of HepG2 tissue lysate at a concentration of 0.25ug/ml.Immunohistochemistry: ST3GAL4 Antibody [NBP1-69565] - Human Liver cells.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

1 Publication
NBP2-22106
Western Blot: PPAR gamma/NR1C3 Antibody [NBP2-22106] - Total protein from 3T3-L1 mouse embryonic fibroblast adipose-like cell line, separated by 4-12% SDS-PAGE, transferred to nitrocellulose membrane and blocked in 5% non-fat milk for 1h at room temperature. The membrane was probed with anti-PPAR gamma 1:800 in non-fat milk. Lane 2-7 increasing protein concentration, undifferentiated adipocytes. Lane 8-13 increasing protein concentration, differentiated adipocytes. This image was submitted via customer review.Immunohistochemistry-Paraffin: PPAR gamma Antibody [NBP2-22106] - IHC analysis of PPAR gamma in mouse liver.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IHC, IHC-P

     1 Review

3 Publications
7270-IL/CF


Species Human

NBP1-90044
Immunocytochemistry/Immunofluorescence: ATN1 Antibody [NBP1-90044] - Staining of human cell line U-251 MG shows localization to nucleoplasm. Antibody staining is shown in green.Immunohistochemistry-Paraffin: ATN1 Antibody [NBP1-90044] - Staining of human liver shows no positivity in hepatocytes as expected.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

1 Publication
NBP1-85010
Western Blot: DMPK Antibody [NBP1-85010] - Analysis in human cell lines U-251MG and Caco-2 using Anti-DMPK antibody. Corresponding DMPK RNA-seq data are presented for the same cell lines. Loading control: Anti-GAPDH.Immunohistochemistry-Paraffin: DMPK Antibody [NBP1-85010] - Staining in human smooth muscle and liver tissues using anti-DMPK antibody. Corresponding DMPK RNA-seq data are presented for the same tissues.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NBP2-67726
Western Blot: Insulin R/CD220 Antibody (SN20-13) - alpha-subunit [NBP2-67726] - Insulin Receptor Antibody (SN20-13) [NBP2-67726] - Analysis of Insulin Receptor on different lysates using anti-Insulin Receptor antibody at 1/1,000 dilution. Positive control: Lane 1: 293 Lane 2: MCF-7 Lane 3: HelaImmunocytochemistry/Immunofluorescence: Insulin R/CD220 Antibody (SN20-13) - alpha-subunit [NBP2-67726] - Insulin Receptor Antibody (SN20-13) [NBP2-67726] - Staining Insulin Receptor in PANC-1 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Rabbit Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF

291-G1
1 μg/lane of Recombinant Human IGF-I was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 7 kDa.Recombinant Human IGF-I (Catalog # 291-G1) stimulates proliferation in the MCF-7 human breast cancer cell line. The ED<SUB>50</SUB> for this effect is 0.3‑1.5 ng/mL.


Species Human

     3 Reviews

108 Publications
NBP1-30027
Western Blot: Serpin A8/Angiotensinogen Antibody [NBP1-30027] - Analysis of Angiotensinogen in human kidney lysate.Immunocytochemistry/Immunofluorescence: Serpin A8/Angiotensinogen Antibody [NBP1-30027] - HepG2 cells were fixed for 10 minutes using 10% formalin and then permeabilized for 5 minutes using 1X TBS + 0.5% Triton-X100. The cells were incubated with anti-Angiotensinogen at 10 ug/ml overnight at 4C and detected with an anti-rabbit Dylight 488 (Green) at a 1:500 dilution. Alpha tubulin (DM1A) NB100-690 was used as a co-stain at a 1:1000 dilution and detected with an anti-mouse Dylight 550 (Red) at a 1:500 dilution. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 40X objective.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

6 Publications
NBP2-69822
Human Copeptin ELISA Kit (Colorimetric) - Standard Curve Reference


Species Human

NBP2-34294
Immunohistochemistry-Paraffin: Thyroglobulin Antibody (2H11+6E1) [NBP2-34294] - Thyroglobulin staining in thyroid tissue of normal C57 mouse (Red). Dilution is 1:100. This image was submitted via customer Review.Immunohistochemistry-Paraffin: Thyroglobulin Antibody (2H11+6E1) [NBP2-34294] - Analysis using Azide/BSA FREE version of NBP2-34294. Human Thyroid stained with Thyroglobulin Ab (2H11 + 6E1).

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, IHC

     2 Reviews

NBP1-47778
Western Blot: Glucokinase/GCK Antibody (3E3) [NBP1-47778] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GCK (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GCK.Immunocytochemistry/Immunofluorescence: Glucokinase/GCK Antibody (3E3) [NBP1-47778] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY GCK.

Mouse Monoclonal
Species Human
Applications WB, ICC/IF, IHC


Related Genes

Diabetes Mellitus has been researched against:

Alternate Names

Diabetes Mellitus is also known as diabetes mellitus, diabetes, diabetes mellitus (disorder), diabetes nos.