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Common Variable Immunodeficiency: Disease Bioinformatics

Research of Common Variable Immunodeficiency has been linked to Immunologic Deficiency Syndromes, Agammaglobulinemia, Infective Disorder, Hypogammaglobulinemia, Autoimmune Reaction. The study of Common Variable Immunodeficiency has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Common Variable Immunodeficiency include Pathogenesis, Secretion, Immunoglobulin Production, Immune Response, Cell Differentiation. These pathways complement our catalog of research reagents for the study of Common Variable Immunodeficiency including antibodies and ELISA kits against SEVERE COMBINED IMMUNODEFICIENCY, CD3, BTK, CD4, CD8A.

Common Variable Immunodeficiency Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Common Variable Immunodeficiency below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 3246 products for the study of Common Variable Immunodeficiency that can be applied to Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NB100-56516
Western Blot: TACI/TNFRSF13B/CVID Antibody [NB100-56516] - Analysis of  A) human spleen, B) mouse spleen, C) human stomach, D) and mouse stomach lysate using TACI antibody at 2 ug/ml.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IHC

7 Publications
202-IL/CF
Recombinant Human IL-2 (Catalog # 202-IL/CF) stimulates cell proliferation of the CTLL‑2 mouse cytotoxic T cell line. The ED<SUB>50</SUB> for this effect is 0.05-0.25 ng/mL.1 μg/lane of Recombinant Human IL-2 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 13 kDa.


Species Human

207 Publications
AF-386-PB
CTLA‑4 was detected in immersion fixed human peripheral blood mononuclear cells treated with treated with PMA and calcium ionomycin using Goat Anti-Human CTLA‑4 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF-386-PB) at 15 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # <a class=    Western  blot shows lysates of NS0 mouse myeloma cell line either mock transfected or  transfected with human <br>CTLA-4. PVDF membrane was probed with  0.5 µg/mL of Goat Anti-Human CTLA‑4 Antigen  Affinity-purified Polyclonal Antibody (Catalog # AF-386-PB) followed by  HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=

Goat Polyclonal
Species Human
Applications WB, Flow, CyTOF-ready

     2 Reviews

2 Publications
210-TA/CF
Recombinant Human TNF-alpha  (Catalog # 210‑TA/CF) induces cytotoxicity in the L-929 mouse fibroblast cell line in the presence of the metabolic inhibitor actinomycin D. The ED<sub>50</sub> for this effect is 25‑100 pg/mL.1 µg/lane of Recombinant Human TNF-alpha  was resolved by SDS-PAGE with silver staining, under reducing (R) conditions, showing a band at 17 kDa.


Species Human

428 Publications
204-IL/CF
1 μg/lane of Recombinant Human IL-4 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 14 kDa.Recombinant Human IL-4 (Catalog # 204‑IL/CF) stimulates cell proliferation of the TF-1 human erythroleukemic cell line. The ED<SUB>50</SUB> for this effect is 0.05‑02 ng/mL.


Species Human

259 Publications
NBP1-19371
Western Blot: CD4 Antibody [NBP1-19371] - CD4 antibody was tested in the following cell lysates: Lane 1) human spleen 2) human tonsil 3) human placenta 4) human kidney 5) human liver 6) mouse spleen 7) mouse placenta 8) rat placenta.Immunocytochemistry/Immunofluorescence: CD4 Antibody [NBP1-19371] - CD4 antibody was tested in Jurkat cells with Dylight 488 (green). Nuclei were counterstained with DAPI (blue).

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ICC/IF

     6 Reviews

13 Publications
NBP2-12499
Immunohistochemistry-Paraffin: ICOS Antibody (SP98) [NBP2-12499] - Human Reactive Lymph NodeImmunohistochemistry-Paraffin: ICOS Antibody (SP98) [NBP2-12499] - Human Tonsil.

Rabbit Monoclonal
Species Human
Applications IHC, IHC-P

NB100-524
Western Blot: NOD2 Antibody (2D9) [NB100-524] - Total protein from human THP1 and US-OS cells and mouse Raw264.7 cells was separated on a 7.5% gel by SDS-PAGE, transferred to PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 2.0 ug/ml anti-NOD2 in 1% non-fat milk in TBST and detected with an anti-mouse HRP secondary antibody using chemiluminescence.Immunocytochemistry/Immunofluorescence: NOD2 Antibody (2D9) [NB100-524] - A431 cells were fixed for 10 minutes using 10% formalin and then permeabilized for 5 minutes using 1X TBS + 0.5% Triton-X100. The cells were incubated with anti-NOD2 (2D9) NB100-524 at a 1:200 dilution overnight at 4C and detected with an anti-mouse Dylight 488 (Green) at a 1:500 dilution. Actin was counterstained with Phalloidin 568 (Red) at a 1:200 dilution. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 40X objective.

Mouse Monoclonal
Species Human, Mouse
Applications WB, Flow, ICC/IF

     1 Review

13 Publications
H00003117-M01
Proximity Ligation Assay: HLA DQA1 Antibody (1A3) [H00003117-M01] - Analysis of protein-protein interactions between CD74 and HLA-DQA1. HeLa cells were stained with anti-CD74 rabbit purified polyclonal 1:1200 and anti-HLA-DQA1 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).ELISA: HLA DQA1 Antibody (1A3) [H00003117-M01] - Detection limit for recombinant GST tagged HLA-DQA1 is 0.3 ng/ml as a capture antibody.

Mouse Monoclonal
Species Human
Applications WB, ELISA, PLA

NBP1-78295
Western Blot: BTK [p Tyr223] Antibody [NBP1-78295] - WB analysis of BTKpY223 on Ramos whole cell lysate with peptide competition: 1. ab only, 2. 200 molar excess unmodified immunizing peptide and 3. 200 molar excess modified immunizing peptide.Immunohistochemistry: BTK [p Tyr223] Antibody [NBP1-78295] - IHC analysis of BTK in kidney cancer xenograft using DAB with hematoxylin counterstain.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, Flow, ICC/IF

3 Publications
NBP1-49045
Immunocytochemistry: CD8 alpha Antibody (53-6.7) [NBP1-49045] - Analysis of immersion fixed splenocytes. Primary antibody was used at a dilution of 10 ug/ml and incubated for 3 hours at room temperature.Immunohistochemistry-Frozen: CD8 alpha Antibody (53-6.7) [NBP1-49045] - Analysis of CD8+ T cells in allogeneic skin grafted onto a mouse.

Rat Monoclonal
Species Mouse, Rat
Applications Flow, ICC/IF, IHC

     2 Reviews

9 Publications
NBP2-25196
Immunocytochemistry/Immunofluorescence: CD19 Antibody (CB19) [NBP2-25196] - The CD19 (CB19) antibody was tested in Daudi cells at a 1:40 dilution against Dylight 488 (Green). Actin and nuclei were counterstained against Phalloidin 568 (Red) and DAPI (Blue), respectively.Flow Cytometry: CD19 Antibody (CB19) [NBP2-25196] - A surface stain was performed on human peripheral blood lymphocytes with CD9 (HI9a) antibody NB100-77915AF647 and a matched isotype control NBP2-27287AF488. Cells were incubated in an antibody dilution of 1 ug/mL for 20 minutes at room temperature. A co-stain was performed with NBP2-26646.

Mouse Monoclonal
Species Human, Mouse
Applications WB, Flow, ICC/IF

10 Publications
AF382
    CD27/TNFRSF7  was detected in immersion fixed paraffin-embedded sections of human tonsil  using Goat Anti-Human CD27/TNFRSF7 Antigen Affinity-purified Polyclonal  Antibody (Catalog # AF382) at 3 µg/mL overnight at  4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell  & Tissue Staining Kit  (brown;  Catalog # <a class=    Western  blot shows lysates of Raji human Burkitt's lymphoma cell line, Daudi human  Burkitt's lymphoma cell line, Ramos human Burkitt's lymphoma cell line, and  human tonsil tissue. PVDF membrane was probed with 1 µg/mL of Goat  Anti-Human CD27/TNFRSF7 Antigen Affinity-purified Polyclonal Antibody  (Catalog # AF382) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody  (Catalog # <a class=

Goat Polyclonal
Species Human
Applications WB, Simple Western, Flow

     1 Review

2 Publications
AF1162
Recombinant Human BAFF R/TNFRSF13C Fc Chimera (Catalog #<br><a class=  Peripheral  blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD19  Fluorescein‑conjugated Monoclonal Antibody (Catalog #  <a class=

Goat Polyclonal
Species Human
Applications WB, Flow, CyTOF-ready

12 Publications
MAB4909
Western blot shows lysates of human spleen tissue. PVDF Membrane was probed with 2 µg/mL of Mouse Anti-Human CD21 Monoclonal Antibody (Catalog # MAB4909) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # <a class=Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD19 PE‑conjugated Monoclonal Antibody (Catalog # <a class=

Mouse Monoclonal
Species Human
Applications WB, Flow, CyTOF-ready

1 Publication

Related Genes

Common Variable Immunodeficiency has been researched against:

Related PTMs

Common Variable Immunodeficiency has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Common Variable Immunodeficiency is also known as common variable immunodeficiency, cvid, common variable immune deficiency, acquired hypogammaglobulinemia, common variable agammaglobulinemia (disorder), common variable hypogamma-globulinemia, immunoglobulin deficiency, late-onset, immunodeficiency, common variable, immunologic deficiency syndromes, hypogamma-globulinemia, acquired, sporadic hypogammaglobulinemia, acquired agammaglobulinemia, immunologic deficiency.