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Colorectal Cancer: Disease Bioinformatics

Colorectal cancer, commonly referred to as colon cancer, originates in the colon (large intestine) or rectum, typically as adenomatous polyps. It is unknown what causes cancer yet familial adenomatous polposis (FAP) and hereditary nonpolyposis colorectal cancer (HNPCC) are thought to increase risk of developing colon cancer. Additionally, increasing age, inflammatory intestinal conditions, nationality, low fiber and high fat diet, diabetes, smoking, alcohol, obesity, and a sedentary lifestyle can contribute to its onset. Treatments for colon cancer include surgery, chemotherapy, radiation therapy, and targeted drug therapy.

Colorectal Cancer Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Colorectal Cancer below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 2038 products for the study of Colorectal Cancer that can be applied to Western Blot, Chromatin Immunoprecipitation, Immunocytochemistry/Immunofluorescence, Flow Cytometry, Chromatin Immunoprecipitation (ChIP), Immunohistochemistry from our catalog of antibodies and ELISA kits.

NB100-56552
Western Blot: MLH1 Antibody (164C819) [NB100-56552] - Analysis of MLH1 in Daudi cell lysate using this antibody at 2 ug/ml.

Mouse Monoclonal
Species Human
Applications WB

NB100-621
Western Blot: MSH2 Antibody [NB100-621] - Detection of Human and Mouse MSH2 by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa, 293T, and mouse NIH3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-MSH2 antibody NB100-621 used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.Immunohistochemistry-Paraffin: MSH2 Antibody [NB100-621] - FFPE section of mouse renal cell carcinoma. Antibody:Affinity purified rabbit anti-MSH2 used at a dilution of 1:1,000 (1ug/ml). Detection: DAB

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IHC, IHC-P

AF1095
Western blot shows lysates of A431 human epithelial carcinoma cell line untreated<br>(‑) or treated (+) with 100 μM pervanadate (PV) for 10 minutes. PVDF membrane was probed with 0.2 µg/mL of Rabbit Anti-Human Phospho-EGFR (Y1173) Antigen Affinity-purified Polyclonal Antibody, followed by HRP-conjugated Anti-Rabbit IgG Secondary Antibody (Catalog # <a class=EGFR phosphorylated at Y1173 was detected in immersion fixed frozen sections of mouse embryo using Rabbit Anti-Human Phospho-EGFR (Y1173) Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1095) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Rabbit HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <a class=

Rabbit Polyclonal
Species Human
Applications WB, Simple Western, IHC

5 Publications
NB200-103
Western Blot: p53 Antibody (PAb 240) [NB200-103] - WB analysis of p53 in MCF7 and HeLa lystates. Image courtesy of anonymous customer product review.Immunocytochemistry/Immunofluorescence: p53 Antibody (PAb 240) [NB200-103] - HeLa cells were fixed for 10 minutes using 10% formalin and then permeabilized for 5 minutes using 1X TBS + 0.5% Triton-X100. The cells were incubated with anti-p53 (PAb 240) [NB200-103] at a 1:200 dilution overnight at 4C and detected with an anti-mouse Dylight 488 (Green) at a 1:500 dilution. Actin was detected with Phalloidin 568 (Red) at a 1:200 dilution. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 40X objective.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ELISA, Flow

     2 Reviews

22 Publications
NB100-91662
Western Blot: APC Antibody [NB100-91662] - Lane1:Hela cell lysate.  Lane2:HEK293T cell lysate.  Lane3:Rat testis tissue lysate.  Immunohistochemistry-Paraffin: APC Antibody [NB100-91662] - IHC-P analysis of a formalin fixed paraffin embedded tissue section of human colon cancer xenograft using 1: 50 dilution of APC antibody.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

NBP2-46231
Western Blot: CEACAM-5/CD66e Antibody (3D8) [NBP2-46231] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CEACAM-5.Immunohistochemistry: CEACAM-5/CD66e Antibody (3D8) [NBP2-46231] - Analysis of Human tonsil tissue.

Mouse Monoclonal
Species Human
Applications WB, IHC

AF4478
Western blot shows lysates of LNCaP human prostate cancer cell line, HeLa human cervical epithelial carcinoma cell line and human liver tissue. PVDF membrane was probed with 1 µg/mL of Sheep Anti-Human CEACAM‑7 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4478) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # <A class=NoLineLink href=    CEACAM‑7  was detected in immersion fixed paraffin-embedded sections of human colon  cancer tissue using Sheep Anti-Human CEACAM‑7 Antigen  Affinity-purified Polyclonal Antibody (Catalog # AF4478) at  3 µg/mL overnight at 4 °C. Tissue was  stained using the Anti-Sheep HRP-DAB Cell & Tissue Staining Kit  (brown; Catalog # <a class=

Sheep Polyclonal
Species Human
Applications WB, IHC

H00005670-T01
Lane 1: PSG2 transfected lysate (36.96 KDa) Lane 2: Non-transfected lysate.PSG2 transfected lysate.


Species Human

H00003845-M01
Western Blot: KRAS Antibody (3B10-2F2) [H00003845-M01] - KRAS monoclonal antibody (M01), clone 3B10-2F2 Analysis of KRAS expression in HeLa.Immunocytochemistry/Immunofluorescence: KRAS Antibody (3B10-2F2) [H00003845-M01] - Analysis of monoclonal antibody to KRAS on HeLa cell. Antibody concentration 10 ug/ml.

Mouse Monoclonal
Species Human
Applications WB, ELISA, ICC/IF

     1 Review

7 Publications
NB100-689
Immunohistochemistry-Paraffin: COX-2 Antibody [NB100-689] - Formalin fixed paraffin embedded colon carcinoma stained with COX-2 antibody.Immunohistochemistry-Paraffin: COX-2 Antibody [NB100-689] - Formalin fixed paraffin embedded human colon carcinoma stained with COX2 antibody.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, IHC

     1 Review

14 Publications
AF4885

Sheep Polyclonal
Species Mouse
Applications WB, IP

1 Publication
NBP2-34390

Mouse Monoclonal
Species Human
Applications WB, Flow, ICC/IF

     1 Review

NBP2-42864
Western Blot: HRAS Antibody [NBP2-42864] - Various whole cell extracts (30 ug) were separated by 12% SDS-PAGE, and the membranes were blotted with H-Ras antibody diluted at 1:500.Immunocytochemistry/Immunofluorescence: HRAS Antibody [NBP2-42864] - Analysis of paraformaldehyde-fixed HeLa, using H-Ras antibody at 1:200 dilution.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

NBP2-29463
Immunohistochemistry-Paraffin: p21/CIP1/CDKN1A Antibody (WA-1 (HJ21)) [NBP2-29463] - Formalin-fixed, paraffin-embedded human bladder carcinoma stained with p21 Monoclonal Antibody (WA-1).

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

11 Publications
NBP1-89942
Western Blot: B-Raf Antibody [NBP1-89942] - Analysis in human cell line MOLT-4.Immunohistochemistry-Paraffin: B-Raf Antibody [NBP1-89942] - Immunohistochemical staining of human kidney shows moderate cytoplasmic positivity in distal tubules.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, IHC

1 Publication
NB200-111
Western Blot: p14ARF/CDKN2A Antibody [NB200-111] - WB analysis of HeLa Whole Cell Lysate (NB800-PC1) using p14ARF antibody (lot C) employing ECL detection method.Immunocytochemistry/Immunofluorescence: p14ARF Antibody [NB200-111] - p14ARF antibody was tested in HeLa cells with Dylight 488 (green). Nuclei were counterstained with DAPI (blue). Tubulin was stained with alpha tubulin (red).

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ELISA, Flow

     2 Reviews

16 Publications

Alternate Names

Colorectal Cancer is also known as colorectal cancer, carcinoma of the large intestine.