Submit your image related to Diseases to be featured!

Get Social

Submit your Twitter account related to Cataplexy And Narcolepsy to be featured!

Blogs

Submit your blog on Cataplexy And Narcolepsy to be featured!

Events

Submit your event on Cataplexy And Narcolepsy to be featured!

Videos

Submit your video on Cataplexy And Narcolepsy to be featured!

Charities

Submit your charity on Cataplexy And Narcolepsy to be featured!

Cataplexy And Narcolepsy: Disease Bioinformatics

Narcolepsy is a neurological disorder affecting the part of the brain that regulates sleep. Those suffering from narcolepsy can experience excessive daytime sleepiness, hallucinations, and sudden loss of muscle control. A normal sleep cycle is about 100 to 110 minutes, beginning with NREM (non rapid eye movement) sleep and transitioning to REM(rapid eye movement) sleep after 80 to 100 minutes. People with narcolepsy frequently enter REM sleep within a few minutes of falling asleep. Narcolepsy effects both men and women equally and is widespread throughout the world. It mostly begins during a person’s childhood and is lifelong. Diagnosis of the condition can take a long time in most cases more than a year and sometimes as long as several decades because narcolepsy symptoms are often mistakenly linked to other sleep disorders or medical conditions such as depression. The only unique symptom of narcolepsy is cataplexy this happens when you lose the ability to control your muscles. Narcolepsy with cataplexy is estimated to affect about one in every 2,000 people in the USA. When cataplexy is present, narcolepsy is almost always caused by the lack of a brain neurotransmitters called hypocretin. Neurotransmitters are chemicals that neurons produce to communicate with each other. Loss of hypocretin results in an inability to regulate sleep. In cases without cataplexy, the disorder may be caused by a lack of hypocretin or by various other causes. People with narcolepsy can fight off the urge to fall asleep with exercise this will keep your heart rate elevated and more awake during the day.

Cataplexy And Narcolepsy Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Cataplexy And Narcolepsy below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 933 products for the study of Cataplexy And Narcolepsy that can be applied to Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

MAB763

Mouse Monoclonal
Species Human, Mouse, Rat
Applications IHC

11 Publications
NBP2-42388
Western Blot: LAMC2 Antibody (CL2980) [NBP2-42388] - Analysis in A-431 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-LAMC2 antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.Immunocytochemistry/Immunofluorescence: LAMC2 Antibody (CL2980) [NBP2-42388] - Staining of A-431 cells using the Anti-LAMC2 monoclonal antibody, showing specific staining in the cytosol in green. Microtubule- and nuclear probes are visualized in red and blue, respectively (where available).

Mouse Monoclonal
Species Human
Applications WB, ICC/IF, IHC

2 Publications
7954-GM/CF


Species Human

1 Publication
H00028954-B01P
Western Blot: REM1 Antibody [H00028954-B01P] - Analysis of REM1 expression in transfected 293T cell line by REM1 polyclonal antibody.  Lane 1: REM1 transfected lysate(32.78 KDa). Lane 2: Non-transfected lysate.Immunocytochemistry/Immunofluorescence: REM1 Antibody [H00028954-B01P] - Analysis of purified antibody to REM1 on HeLa cell. (antibody concentration 10 ug/ml)

Mouse Polyclonal
Species Human
Applications WB, ELISA, ICC/IF

H00003126-M01
Western Blot: HLA DRB4 Antibody (4C8) [H00003126-M01] - HLA-DRB4 monoclonal antibody (M01), clone 4C8. Analysis of HLA-DRB4 expression in human kidney.Immunohistochemistry-Paraffin: HLA DRB4 Antibody (4C8) [H00003126-M01] - Analysis of monoclonal antibody to HLA-DRB4 on formalin-fixed paraffin-embedded human tonsil. Antibody concentration 1 ug/ml.

Mouse Monoclonal
Species Human
Applications WB, ELISA, IHC

1 Publication
NBP2-46290
Western Blot: CHN 1 Antibody (2G6) [NBP2-46290] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CHN 1.Immunocytochemistry/Immunofluorescence: CHN 1 Antibody (2G6) [NBP2-46290] - Analysis  of COS7 cells transiently transfected by pCMV6-ENTRY CHN 1.

Mouse Monoclonal
Species Human
Applications WB, ICC/IF, IHC

NBP2-57697
Immunohistochemistry-Paraffin: PMCH Antibody [NBP2-57697] - Staining of human cerebral cortex, hypothalamus, liver and testis using Anti-PMCH antibody NBP2-57697 (A) shows similar protein distribution across tissues to independent antibody NBP2-13780 (B).Immunohistochemistry: PMCH Antibody [NBP2-57697] - Staining of mouse brain shows strong positivity in of neurons in the hypothalamus.

Rabbit Polyclonal
Species Human, Mouse
Applications IHC, IHC-P

NBP2-14984
Western Blot: HLA DQB2 Antibody [NBP2-14984] - Sample (30 ug of whole cell lysate)  A: K562  12% SDS PAGE   diluted at 1:1000 Immunohistochemistry-Paraffin: HLA DQB2 Antibody [NBP2-14984] - Paraffin-embedded Colon ca, using antibody at 1:500 dilution.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NBP1-84549
Western Blot: HLA DQB1 Antibody [NBP1-84549] - Lane 1: Marker  [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG sp.  Lane 4: Human plasma (IgG/HSA depleted).  Lane 5: Human liver tissue.  Lane 6: Human tonsil tissueImmunohistochemistry-Paraffin: HLA DQB1 Antibody [NBP1-84549] - Staining of human lymph node shows strong cytoplasmic positivity in reaction center cells, lymphoid cells outside reaction centra.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NB100-91348
Western Blot: VAChT/SLC18A3 Antibody [NB100-91348] -  Rat and mouse tissue lysates. Blocking: 1% LFDM for 30 min at RT; primary antibody: dilution 1:2000 incubated at 4C overnight.Immunohistochemistry-Paraffin: VAChT/SLC18A3 Antibody [NB100-91348] - Rat spinal cord. The animal was perfused using Autoperfuser at a pressure of 130 mmHg with 300 ml 4% FA before being processed for paraffin embedding. HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered thru 0.2 um.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

NB100-1519
Western Blot: Acetylcholinesterase/ACHE Antibody [NB100-1519] - Staining of HepG2 (A) and Daudi cell lysates with antibody at 1 ug/mL (B) and HeLa (C) and Jurkat (D) cell lysates with antibody at 0.3 ug/mL (35 ug protein in RIPA buffer). Detected by chemiluminescence.Immunocytochemistry/Immunofluorescence: Acetylcholinesterase/ACHE Antibody [NB100-1519] - Immunofluorescence analysis of paraformaldehyde fixed U2OS cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (4 ug/mL), showing cytoplasmic and nuclear/Vesicle staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (4 ug/mL).

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

     1 Review

1 Publication
NB100-1533
Western Blot: POMC Antibody [NB100-1533] - Staining of NIH3T3 cell lysate with antibody at 0.3 ug/mL (A) and Rat Brain cell lysate with antibody at 2 ug/mL (B). 35 ug protein in RIPA buffer. Detected by chemiluminescence.Immunohistochemistry-Paraffin: POMC Antibody [NB100-1533] - Staining of paraffin embedded Human Pituitary Gland. Antibody at 2 ug/mL. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

10 Publications
AF1638
Nucleostemin was detected in immersion fixed U2OS human osteosarcoma cell line using 10 µg/mL Goat Anti-Human/Mouse/Rat Nucleostemin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1638) for 3 hours at room temperature. Cells were stained with the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red, upper panel; Catalog # <a class=Simple Western lane view shows lysates of PC‑3 human prostate cancer cell line, loaded at 0.2 mg/mL. A specific band was detected for Nucleostemin at approximately 83 kDa (as indicated) using 5 µg/mL of Goat Anti-Human/Mouse/Rat Nucleostemin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1638) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary Antibody<br> (Catalog # <a class=

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ICC

5 Publications
H00010908-M08
Western Blot: PNPLA6 Antibody (3D10) [H00010908-M08] - Analysis of PNPLA6 expression in transfected 293T cell line by NTE monoclonal antibody (M08), clone 3D10. Lane 1: PNPLA6 transfected lysate (Predicted MW: 146.2 KDa). Lane 2: Non-transfected lysate.Immunohistochemistry-Paraffin: PNPLA6 Antibody (3D10) [H00010908-M08] - Analysis of monoclonal antibody to PNPLA6 on formalin-fixed paraffin-embedded human small Intestine. Antibody concentration 3 ug/ml

Mouse Monoclonal
Species Human
Applications WB, ELISA, IHC

AF-249-NA
Recombinant Human LIF stimulates proliferation in the TF‑1 human erythroleukemic cell line in a dose-dependent manner (orange line). Proliferation elicited by 0.3 ng/mL Recombinant Human LIF is neutralized (green line) by increasing concentrations of Goat Anti-Human LIF R alpha  Antigen Affinity-purified Polyclonal Antibody (Catalog # AF-249-NA). The ND<SUB>50</SUB> is typically 6-36 µg/mL.

Goat Polyclonal
Species Human
Applications WB, Neut

11 Publications
NBP2-46627
Western Blot: VGLUT1 Antibody (2754) [NBP2-46627] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10.  Lane 2: Human Cerebral Cortex tissueImmunohistochemistry: VGLUT1 Antibody (2754) [NBP2-46627] - Staining of rat brain shows strong positivity in glutamatergic processes in the molecular and granular layers of cerebellum.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P


Related Genes

Cataplexy And Narcolepsy has been researched against:

Related PTMs

Cataplexy And Narcolepsy has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Cataplexy And Narcolepsy is also known as Narcolepsy And Cataplexy, Narcolepsy With Cataplexy, Narcolepsy-cataplexy Syndrome, Syndrome, Narcolepsy-cataplexy.