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Alpha-dystroglycanopathies: Disease Bioinformatics

Research of Alpha-dystroglycanopathies has been linked to Muscular Dystrophy, Dystrophy, Congenital Muscular Dystrophy (disorder), Walker-warburg Congenital Muscular Dystrophy, Congenital Anomaly Of Brain. The study of Alpha-dystroglycanopathies has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Alpha-dystroglycanopathies include Glycosylation, Protein Glycosylation, Regeneration, Mrna Splicing. These pathways complement our catalog of research reagents for the study of Alpha-dystroglycanopathies including antibodies and ELISA kits against FKTN, POMGNT1, ALPHA-DYSTROGLYCAN, POMT1, DAG1.

Alpha-dystroglycanopathies Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Alpha-dystroglycanopathies below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 182 products for the study of Alpha-dystroglycanopathies that can be applied to Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

NBP1-33383
Western Blot: FKTN Antibody [NBP1-33383] - Sample (30 ug of whole cell lysate) A: H1299 B: Hela 10% SDS PAGE; antibody diluted at 1:1000.Immunocytochemistry/Immunofluorescence: FKTN Antibody [NBP1-33383] - Methanol-fixed HeLa, using FKTN antibody at 1:200 dilution.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF

NBP1-52030
Western Blot: MYF6 Antibody [NBP1-52030] - HEK293 lysate (10ug protein in RIPA buffer) overexpressing Human MYF6 with MYC tag probed with EB09957 (0.5ug/ml) in Lane A and probed with anti-MYC Tag (1/1000) in lane C. Mock-transfected HEK293 probed with EB09957 (0.5mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence.

Goat Polyclonal
Species Human
Applications WB, PEP-ELISA

1 Publication
NBP1-79722
Western Blot: ISPD Antibody [NBP1-79722] - Human Lung lysate, concentration 0.2-1 ug/ml.

Rabbit Polyclonal
Species Human
Applications WB

NBP1-83257
Western Blot: HINT1 Antibody [NBP1-83257] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).Immunocytochemistry/Immunofluorescence: HINT1 Antibody [NBP1-83257] - Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

NBP1-85630
Western Blot: Choline kinase alpha Antibody [NBP1-85630] - Analysis in human cell lines SK-MEL-30 and U-251MG using anti-CHKA antibody. Corresponding CHKA RNA-seq data are presented for the same cell lines. Loading control: anti-HDAC1.Immunohistochemistry-Paraffin: Choline kinase alpha Antibody [NBP1-85630] -  Staining of human gastrointestinal shows moderate cytoplasmic positivity in glandular cells.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

1 Publication
NBP1-86152
Western Blot: POMT2 Antibody [NBP1-86152] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).Immunohistochemistry-Paraffin: POMT2 Antibody [NBP1-86152] - Staining of human prostate shows strong granular cytoplasmic positivity in glandular cells.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

NBP2-14868
Western Blot: Dystroglycan Antibody [NBP2-14868] - Various tissue extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with Dystroglycan Antibody diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.Immunocytochemistry/Immunofluorescence: Dystroglycan Antibody [NBP2-14868] - HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Dystroglycan protein stained by Dystroglycan antibody 38) diluted at 1:1000. Red: alpha Tubulin, a cytoskeleton marker, stained by alpha Tubulin antibody [B-5-1-2]  diluted at 1:10000. Blue: Hoechst 33342 staining.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

2 Publications
NBP2-22321
Western Blot: GOLGB1/Giantin Antibody [NBP2-22321] - HeLa cell lysate sample treated with DMSO was run on 8% SDS-PAGE. Both giantin monomer and  dimer are indicated. Western blot image submitted by a verified customer review.Immunocytochemistry/Immunofluorescence: GOLGB1/Giantin Antibody [NBP2-22321] - PC-3 human prostate cancer cell line. Image was captured using EVOS M5000 microscope. Red - giantin; blue - nucleus, DAPI; bar 40 micron. ICC/IF image submitted by a verified customer review.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IP

     2 Reviews

5 Publications
NBP2-56655
Western Blot: TMEM5 Antibody [NBP2-56655] - Western blot analysis in human cell line RT-4 and human cell line U-251 MG.Immunocytochemistry/Immunofluorescence: TMEM5 Antibody [NBP2-56655] - Staining of human cell line A549 shows localization to the Golgi apparatus.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF

H00004595-M01
Knockdown Validated: MYH Antibody (4D10) [H00004595-M01] - Simultaneous suppression of MTH1 and MYH was efficiently achieved using a two-vector system. To investigate the knockdown efficiency at protein level, western blot analysis was performed after 96 hrs of Dox treatment of cells with shRNA set1 (d). Data were double normalized with GAPDH and NT-shRNA control samples and expressed as percentage. The graphs represent mean +/-s.e.m. from three independent experiments. P-values were calculated using one-way analysis of variance (ANOVA). *P<0.05, **P<0.01, ***P<0.001, NS, not significant. Image collected and cropped by CiteAb from the following publication (http://www.nature.com/articles/oncsis201672) licensed under a CC-BY licence.Western Blot: MYH Antibody (4D10) [H00004595-M01] - Analysis of MUTYH expression in transfected 293T cell line by MUTYH monoclonal antibody (M01), clone 4D10.Lane 1: MUTYH transfected lysate(59.1 KDa).Lane 2: Non-transfected lysate.

Mouse Monoclonal
Species Human, Mouse
Applications WB, ELISA, ICC/IF

10 Publications
NBP1-05034
Western Blot: DPM1 Antibody [NBP1-05034] - (0.1ug/ml) staining of Human Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Immunohistochemistry-Paraffin: DPM1 Antibody [NBP1-05034] - (3.75ug/ml) staining of paraffin embedded Human Tonsil. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Goat Polyclonal
Species Human
Applications WB, IHC, IHC-P

1 Publication
NBP3-04945
Western Blot: FKRP Antibody [NBP3-04945] - Analysis of extracts of various cell lines, using FKRP antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

NBP2-93413
Western Blot: POMT1 Antibody [NBP2-93413] - Analysis of extracts of various cell lines, using POMT1 at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit . Exposure time: 5s.

Rabbit Polyclonal
Species Human, Mouse
Applications WB

NBP2-93561
Western Blot: POMGNT1 Antibody [NBP2-93561] - Analysis of extracts of various cell lines, using POMGNT1 at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit . Exposure time: 60s.Immunohistochemistry-Paraffin: POMGNT1 Antibody [NBP2-93561] - Paraffin-embedded human prostate using POMGNT1 .

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P


Related Genes

Alpha-dystroglycanopathies has been researched against:

Related Pathways

Alpha-dystroglycanopathies has been linked to:

Related PTMs

Alpha-dystroglycanopathies has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Alpha-dystroglycanopathies is also known as Alpha Dystroglycanopathies.