Acute Myeloid Leukemia is a clonal disorder caused by malignant transformation of a bone marrow-derived, self-renewing stem cell or progenitor. This leads to a decreased rate of self-destruction and aberrant differentiation causing an accumulation in the organs and bone marrow by these myeloid cells. In M1, there is minimal maturation of cells and the prognosis is average for patients with AML. The development of Acute Myeloid Leukemia has been associated with many predisposition syndromes that are caused by chromosomal imbalances, DNA repair defects, altered protein synthesis and altered cytokine receptors or signal transduction pathways.
Acute Myeloid Leukemia, M1 Bioinformatics Tool
Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Acute Myeloid Leukemia, M1 below!
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We have 2441 products for the study of Acute Myeloid Leukemia, M1 that can be applied to Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.
Acute Myeloid Leukemia, M1 is also known as Acute Myeloblastic Leukemia M1, Acute Myeloblastic Leukemia Without Maturation, Acute Myelocytic Leukemia Without Maturation, Acute Myeloid Leukaemia Without Maturation, Acute Myeloid Leukemia Without Maturation.