Zic2 Products

Description

This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13.

Bioinformatics

Entrez	7546 Human
Uniprot	NP_009060 Human
Product By Gene ID	7546
Alternate Names	HPE5Zic family member 2 (odd-paired Drosophila homolog) Zic family member 2 (odd-paired homolog, Drosophila) Zinc finger protein of the cerebellum 2 zinc finger protein ZIC 2

Research Areas for Zic2

Find related products by research area and learn more about each of the different research areas below.

Growth and Development
Neuronal Cell Markers
Neuroscience
Signal Transduction
Transcription Factors and Regulators