XAGE3 Products

Description

XAGE3 is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is expressed in placenta and fetal liver/spleen, and may function in inhibiting cancer cell growth. The protein encoded by this gene shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of this gene generates 2 transcript variants differing in the 5' UTR. [provided by RefSeq]. Transcript Variant: This variant (1) has an alternate exon 1, as compared to variant 2. It thus has a different and longer 5' UTR, but encodes the same protein as variant 2.

Bioinformatics

Entrez	170626 Human
Uniprot	NM_133179 Human NP_570132 Human
Product By Gene ID	170626
Alternate Names	Cancer/testis antigen 12.3 cancer/testis antigen family 12, member 3a cancer/testis antigen family 12, member 3b CT12.3 CT12.3a CT12.3b G antigen family D member 4 G antigen, family D, 4 MGC71925 PLAC6GAGED4 placenta-specific 6 placenta-specific 6; G antigen, family D, 4 Placenta-specific gene 6 protein pp9012 Protein XAGE-3 X antigen family, member 3 XAGE-3