WDR45 Products


Description

WDR45 encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene has a pseudogene at chromosome 4q31.3. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity and full-length nature of some variants have not been determined. [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 11152
Alternate Names
  • JM5
  • WD repeat domain 45
  • WD repeat domain phosphoinositide-interacting protein 4
  • WD repeat-containing protein 45
  • WD45 repeat protein interacting with phosphoinositides 4
  • WDRX1
  • WDRXI4
  • WIPI-4
  • X-linked 1