USP21 Products

Description

USP21 encodes a member of the C19 peptidase family, also known as family 2 of ubiquitin carboxy-terminal hydrolases. The encoded protein cleaves ubiquitin from ubiquitinated proteins for recycling in intracellular protein degradation. The encoded protein is also able to release NEDD8, a ubiquitin-like protein, from NEDD8-conjugated proteins. This gene has been referred to as USP16 and USP23 but is now known as USP21. Alternatively spliced transcript variants have been described.

Bioinformatics

Entrez	27005 Human
Uniprot	NP_036607 Human NP_001014443 Human AAH90946.1 Human
Product By Gene ID	27005
Alternate Names	EC 3.1.2.15 MGC3394 EC 3.4.19.12 Ubiquitin-specific-processing protease 21 ubiquitin-specific protease 16 Ubiquitin thiolesterase 21 ubiquitin-specific processing protease 21 Deubiquitinating enzyme 21 ubiquitin thioesterase 21 ubiquitin specific protease 21 ubiquitin carboxyl-terminal hydrolase 21 USP16 USP23NEDD8-specific protease ubiquitin specific peptidase 21

Diseases related to USP21

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Insulin Resistance
Diabetes Mellitus, Non-insulin-dependent
Diabetes Mellitus
Hypokinesia

Pathways for USP21

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Localization
Methylation
Regeneration
Insulin Secretion
Cell Growth
Histone Modification
Regulation Of Cell Growth
Nuclear Export
Conjugation
Secretion

Research Areas for USP21

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Cell Biology
Neuroscience
Ubiquitin Proteasome Pathway

PTMs for USP21

Learn more about PTMs related to USP21.

Methylation
Ubiquitination
Phosphorylation
Reduction
Cleavage
Deacetylation

Bioinformatics Tool for USP21

Discover related pathways, diseases and genes to USP21. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.