UPF2 Products

Antibodies
UPF2 Antibody
UPF2 Antibody
NBP2-22281
Species: Hu, Mu, Bovine, Canine, Equine, Primate, Porcine, Rabbit, Bat
Applications: WB, IP
Host: Rabbit Polyclonal
UPF2 Antibody
UPF2 Antibody
NBP2-20813
Species: Hu, Mu
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
UPF2 Antibody
UPF2 Antibody
NBP1-80460
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
RNAi
UPF2 RNAi
UPF2 RNAi
H00026019-R01
Species: Hu
UPF2 RNAi
UPF2 RNAi
H00026019-R02
Species: Hu

Description

UPF2 encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene; both variants encode the same protein.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Product By Gene ID 26019
Alternate Names
  • DKFZp434D222
  • hUpf2
  • DKFZP434D222
  • yeast Upf2p homolog
  • Up-frameshift suppressor 2 homolog
  • regulator of nonsense transcripts 2
  • Nonsense mRNA reducing factor 2
  • smg-3
  • KIAA1408MGC138835
  • RENT2MGC138834
  • HUPF2
  • UPF2 regulator of nonsense transcripts homolog (yeast)

PTMs for UPF2

Learn more about PTMs related to UPF2.

Phosphorylation
Dephosphorylation
Oxidation
Ribosylation

Bioinformatics Tool for UPF2

Discover related pathways, diseases and genes to UPF2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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