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HAF007). Specific bands were detected for TSH R at approximately 55 and 83 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 7." class="big_lightbox" target="_blank">
MAB65341) coated on a Clear Polystyrene Microplate (Catalog # DY990). Mouse Anti-Human TSH R Monoclonal Antibody (Catalog # MAB6534) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998) followed by Substrate Solution (Catalog # DY999) and stopping the enzymatic reaction with Stop Solution (Catalog # DY994)." class="big_lightbox" target="_blank">
Species: Hu Applications: WB, ELISA Host: Mouse Monoclonal
Thyroid stimulating hormone, also known as thyrotropin, is secreted from cells in the anterior pituitary called thyrotrophs, finds its receptors on epithelial cells in the thyroid gland, and stimulates that gland to synthesize and release thyroid hormones. TSH is a glycoprotein hormone composed of two subunits which are non covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones, follicle stimulating hormone and luteinizing hormone, and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity.
![Western Blot TSHR Antibody (484405) [Unconjugated]](http://images.novusbio.com/images/antibody/TSH_R_MAB6534_Western_Blot_10858.jpg)
![Flow Cytometry TSHR Antibody (484404) [Unconjugated]](http://images.novusbio.com/images/antibody/TSH_R_MAB65342_Flow_Cytometry_21572.jpg)
![ELISA TSHR Antibody (484405) [Unconjugated]](http://images.novusbio.com/images/antibody/TSH_R_MAB6534_ELISA_21565.jpg)
