TDG Products

Antibodies
TDG Antibody (3C11)
TDG Antibody (3C11)
Species: Hu
Applications: WB, IHC, IHC-P
Host: Mouse Monoclonal
TDG Antibody
TDG Antibody
NBP2-13423
Species: Hu, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
TDG Antibody (1142)
TDG Antibody (1142)
NBP2-43595
Species: Hu
Applications: WB, ICC/IF
Host: Mouse Monoclonal
Lysates
TDG Overexpression Lysate (De ...
TDG Overexpression Lysate (Denatured)
H00006996-T01
Species: Hu
Applications: WB
TDG Overexpression Lysate (Na ...
TDG Overexpression Lysate (Native)
NBL1-16797
Applications: WB
Proteins
TDG Recombinant Protein Antig ...
TDG Recombinant Protein Antigen
NBP2-13423PEP
Species: Hu
Applications: AC
TDG Recombinant Protein
TDG Recombinant Protein
NBP2-22863
Species: Hu
Applications: PAGE
RNAi
TDG RNAi
TDG RNAi
H00006996-R01
Species: Hu
TDG RNAi
TDG RNAi
H00006996-R02
Species: Hu

Description

Thymine DNA glycosylase is encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq]

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 6996
Alternate Names
  • EC 3.2.2.29
  • thymine-DNA glycosylaseG/T mismatch-specific thymine DNA glycosylase

Research Areas for TDG

Find related products by research area and learn more about each of the different research areas below.

Base Excision Repair
DNA Repair

Bioinformatics Tool for TDG

Discover related pathways, diseases and genes to TDG. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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