Species: Hu
Applications: Flow, Func, IHC, IP, CyTOF-ready
Host: Mouse Monoclonal
Description
CD3G is encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency.
Bioinformatics
| Uniprot |
Human |
| Product By Gene ID |
6957 |
| Alternate Names |
- T cell receptor beta locus
- T-cell antigen receptor, beta polypeptide, T-cell receptor, beta cluster
- T-cell receptor, beta cluster
- TCRB
- TRB
|