TBX3 Products

Description

Tbx3 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined.

Bioinformatics

Entrez	6926 Human
Uniprot	NM_016569 Human NP_005987 Human NP_057653.3 Human
Product By Gene ID	6926
Alternate Names	bladder cancer related protein XHL T-box 3 T-box protein 3 T-box transcription factor TBX3 TBX3-ISO ulnar mammary syndrome UMS XHL