Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Description
FUNCTION: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. MISCELLANEOUS: Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
259295 |
| Alternate Names |
- MGC119119
- MGC119120
- MGC119121
- MGC134637
- T2R20
- T2R49
- T2R56MGC119118
- TAS2R49
- taste receptor type 2 member 20
- Taste receptor type 2 member 49
- Taste receptor type 2 member 56
- taste receptor, type 2, member 20
- taste receptor, type 2, member 49
|
Research Areas for TAS2R49
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GPCR
