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TAS2R45 Products


Description

FUNCTION: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. MISCELLANEOUS: Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.

Bioinformatics

Entrez
259291
Human
Uniprot
P59539
Human
Product By Gene ID 259291
Alternate Names
  • G protein-coupled receptor 59
  • GPR59
  • G-protein coupled receptor 59
  • MGC119923
  • MGC119924
  • MGC119925
  • T2R45
  • taste receptor type 2 member 45
  • taste receptor, type 2, member 45
  • ZG24P

Research Areas for TAS2R45

Find related products by research area and learn more about each of the different research areas below.

GPCR