TAS2R13 Products

TAS2R13 Overexpression Lysate ...
TAS2R13 Overexpression Lysate (Nat...
Applications: WB
Species: Hu


TAS2R13 product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13. FUNCTION: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells. MISCELLANEOUS: Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli. Useful Links; The Human Olfactory Data Exploratorium: HORDE; Olfactory Receptor Data Base: ORDB; Transmembrane Analysis: TM analysis


Entrez Human
Uniprot Human
Product By Gene ID 50838
Alternate Names
  • taste receptor, family B, member 3
  • taste receptor type 2 member 13
  • T2R13TRB3Taste receptor family B member 3
  • taste receptor, type 2, member 13

Diseases related to TAS2R13

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Malignant Neoplasms
Malignant Neck Neoplasm
Malignant Head And Neck Neoplasm

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