Description
Apoptosis is characterized by a number of intracellular phenomena such as membrane blebbing, chromatin condensation and nuclear DNA fragmentation. Detection of nuclear DNA fragmentation is a widely accepted method to assay for apoptosis and can be performed in situ by incorporating labeled nucleotides onto the free 3' OH ends of DNA fragments using terminal deoxynucleotidyl transferase enzyme (TdT). This type of assay, often referred to as the TUNEL assay, allows monitoring of apoptosis in cell samples or in tissue sections, providing histological localization of apoptotic events.
Research Areas for TACS-XL In Situ
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ApoptosisApoptosis Detections
