Species: Hu
Applications: WB, ELISA, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
SRA is a member of the SR protein family, which interacts with the C-terminal domain of the large subunit of RNA polymerase II and is involved in pre-mRNA splicing. It is a functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. SRA also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2). It enhances cellular proliferation and differentiation, promotes apoptosis in vivo, and may play a role in tumorigenesis.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
|
| Product By Gene ID |
10011 |
| Alternate Names |
- MGC87674
- pp7684
- SRA
- SRAP
- steriod receptor RNA activator 1
- steriod receptor RNA activator protein
- steroid receptor coactivator
- steroid receptor RNA activator 1 (complexes with NCOA1)
- steroid receptor RNA activator 1
- Steroid receptor RNA activator protein
- STRAA1
|
