SPRY3 Products

Description

SPRY3 (sprouty homolog 3) is a member of the sprouty family of proteins. SPRY3 appears to modulate Ras/MAPK pathway signaling following RTK activation. Human SPRY3 is 288 amino acids (aa) in length and contains one SH2-binding domain (aa 25‑30), a PEST sequence (aa 82‑93), and a Cys-rich domain (aa 147‑270). SPRY3 forms homo- and hetero-oligomers with other SPRY family molecules. It also undergoes phosphorylation, ubiquitination and palmitoylation, the latter of which induces SPRY3 to associate with cell membranes.

Bioinformatics

Uniprot	O43610
Product By Gene ID	10251
Alternate Names	Antagonist Of FGF Signaling HSPRY3 Protein Sprouty Homolog 3 sprouty (Drosophila) homolog 2 Sprouty Homolog 3 (Drosophila) SPRY3 spry-3