Species: Mu, Rt
Applications: WB
Host: Rabbit Polyclonal
Description
The protein encoded by the Sodium Potassium ATPase Alpha 4 gene belongs to the family of P-type cation transport ATPases, and to the subfamily ofNa+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining theelectrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential forosmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electricalexcitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and asmaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This geneencodes an alpha 4 subunit. Alternatively spliced transcript variants encoding different isoforms have beenidentified. (provided by RefSeq)
Bioinformatics
Entrez |
Human |
Uniprot |
Human |
Product By Gene ID |
480 |
Alternate Names |
- ATP1A1
- ATP1AL2Na+/K+ ATPase, alpha-D polypeptide
- ATPase, Na+/K+ transporting, alpha 4 polypeptide
- ATPase, Na+/K+ transporting, alpha polypeptide-like 2
- EC 3.6.3
- EC 3.6.3.9
- K-ATPase subunit alpha-C
- MGC25056
- Na
- Na(+)/K(+) ATPase alpha-4 subunit
- Na+/K+ ATPase 4
- sodium pump 4
- Sodium pump subunit alpha-4
- sodium/potassium-transporting ATPase alpha-4 chain
- sodium/potassium-transporting ATPase subunit alpha-4
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