SNAP alpha/beta Products

Description

Alpha, beta and gamma SNAPs, also known as soluble NSF attachment proteins, have apparent molecular weights on SDS PAGE of 35, 36 and 39 kDa, respectively. SNAP proteins mediate the association of NSF to membranes during vesicle fusion reaction, and play a prominent role in synaptic vesicle fusion. In addition, beta SNAP interacts with synaptotagmin and may be involved in calcium regulated exocytosis. SNAP was identified as being required for vesicle fusion in intra Golgi transport reaction in vitro. Alpha SNAP mediates the association of NSF to membranes during vesicle fusion reaction, and plays a prominent role and in synaptic vesicle fusion. Together with synaptotagmin and NSF, alpha SNAP modulates the interaction of SNAP25, VAMP, and syntaxin in, an ATP dependent manner, to form a complex with a sedimentation coefficient of 20 S. This complex may represent an intermediate involved in synaptic vesicle docking and fusion.

Bioinformatics

Entrez	140673 Rat
Product By Gene ID	8775
Alternate Names	alpha-SNAP S SNAPA N-ethylmaleimide-sensitive factor attachment protein alpha SNAP-alpha alpha-soluble NSF attachment protein N-ethylmaleimide-sensitive factor attachment protein, alpha

Diseases related to SNAP alpha/beta

Discover more about diseases related to SNAP alpha/beta.

Cardiac Arrhythmia
Premature Ventricular Contractions
Kidney Failure
Neoplasms
Lupus Erythematosus, Systemic
Kidney Failure, Chronic
Malignant Neoplasms
Poisoning
Tachycardia, Ventricular
Plant Diseases
Lyme Disease
Diabetes Mellitus
Heart Failure
Kidney Diseases
Gastroenteritis
Ventricular Fibrillation
Acute Kidney Injury
Hydrocephalus
Myocardial Infarction
Atrial Flutter

Pathways for SNAP alpha/beta

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Excretion
Transport
Pathogenesis
Virulence
Secretion
Anaerobic Respiration
Electron Transport
Cell Cycle
Localization
Conjugation
Glomerular Filtration
Sensitization
Cell Division
Fermentation
Nitrogen Fixation
Cognition
Spore Germination
Membrane Fusion
Denitrification Pathway
Nitrate Assimilation

PTMs for SNAP alpha/beta

Learn more about PTMs related to SNAP alpha/beta.

Nitration
Acetylation
Oxidation
Phosphorylation
Cleavage
Deacetylation
Ubiquitination
Dephosphorylation
Ribosylation

Bioinformatics Tool for SNAP alpha/beta

Discover related pathways, diseases and genes to SNAP alpha/beta. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.