SLA Class II DQ Products


HLA-DQB1 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of analpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system bypresenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells(APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and it contains 6 exons.Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes thetransmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DQ molecule both the alpha chain and the betachain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 differentmolecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. (provided by RefSeq)


Product By Gene ID 3117
Alternate Names
  • MHC HLA-DQ alpha
  • GSE
  • MHC class II surface glycoprotein
  • FLJ27328
  • MHC class II HLA-DQ-alpha-1
  • FLJ27088
  • MHC class II HLA-D alpha glycoprotein
  • DQ-A1
  • MHC class II antigen
  • CD
  • leukocyte antigen alpha chain
  • MHC class II DQA1
  • leucocyte antigen DQA1
  • DC-1 alpha chain
  • HLA class II histocompatibility antigen, DQ(W3) alpha chain
  • CELIAC1DQ alpha 1 chain
  • MGC149527
  • major histocompatibility complex, class II, DQ alpha 1

PTMs for SLA Class II DQ

Learn more about PTMs related to SLA Class II DQ.


Bioinformatics Tool for SLA Class II DQ

Discover related pathways, diseases and genes to SLA Class II DQ. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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