SIGLECL12 Products

Antibodies
SIGLECL12 Antibody
SIGLECL12 Antibody
NBP2-20362
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
SIGLECL12 Antibody (1D1)
SIGLECL12 Antibody (1D1)
H00089858-M01
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
SIGLECL12 Antibody
SIGLECL12 Antibody
NBP1-59241
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Lysates
SIGLECL12 Overexpression Lysa ...
SIGLECL12 Overexpression Lysate (D...
H00089858-T01
Applications: WB
Proteins
SIGLECL12 Partial Recombinant ...
SIGLECL12 Partial Recombinant Protein
H00089858-Q02
Species: Hu
Applications: WB, ELISA, PA
SIGLECL12 Partial Recombinant ...
SIGLECL12 Partial Recombinant Protein
H00089858-Q01
Species: Hu
Applications: WB, ELISA, PA

Description

Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to theimmunoglobulin superfamily. They mediate protein-carbohydrate interactions by selectively binding to different sialicacid moieties present on glycolipids and glycoproteins. This gene encodes a member of the SIGLEC3-like subfamily ofSIGLECs. Members of this subfamily are characterized by an extracellular V-set immunoglobulin-like domain followed bytwo C2-set immunoglobulin-like domains, and the cytoplasmic tyrosine-based motifs ITIM and SLAM-like. The encodedprotein, upon tyrosine phosphorylation, has been shown to recruit the Src homology 2 domain-containingprotein-tyrosine phosphatases SHP1 and SHP2. It has been suggested that the protein is involved in the negativeregulation of macrophage signaling by functioning as an inhibitory receptor. This gene is located in a cluster withother SIGLEC3-like genes on 19q13.4. Alternatively spliced transcript variants encoding distinct isoforms have beendescribed for this gene. (provided by RefSeq)

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 89858
Alternate Names
  • SIGLEC-like 1
  • sialic acid-binding Ig-like lectin 12
  • Siglec-XII
  • FLJ38600
  • S2V
  • SIGLECL1Sialic acid-binding Ig-like lectin-like 1
  • SLGSiglec-L1
  • Siglec-12
  • sialic acid binding Ig-like lectin 12

Pathways for SIGLECL12

View related products by pathway and learn more about each of the pathways below.

Localization

Bioinformatics Tool for SIGLECL12

Discover related pathways, diseases and genes to SIGLECL12. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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