SERPINB12 Products

Description

Members of the human serpin family regulate a diverse array of serine and cysteine proteinases associated with essential biological processes such as fibrinolysis, coagulation, inflammation, cell mobility, cellular differentiation, and apoptosis. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular fluids. However, a subset of the serpin superfamily, the ov-serpins, also resides intracellularly. A novel member of the human ov-serpin gene family, SERPINB12 is expressed in many tissues, including brain, bone marrow, lymph node, heart, lung, liver, pancreas, testis, ovary, and intestines. SERPINB12 is an inhibitor of trypsin-like serine proteinases and a new functional member of the human ov-serpin family.

Bioinformatics

Entrez	89777 Human
Uniprot	NP_536722 Human Q96P63 Human
Product By Gene ID	89777
Alternate Names	MGC119247 MGC119248 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 12 serpin B12 serpin peptidase inhibitor, clade B (ovalbumin), member 12 YUKOPIN