SERF2 Products

Description

Serf2 (small EDRK-rich factor 2) is the human ortholog of the C. elegans MOAG-4 gene. MOAG-4 was shown to be a positive regulator of protein aggregates. Inactivation of MOAG-4 leads to a rescue from proteotoxcity, and could play a role in human diseases such as Alzheimers disease and Parkinsons disease. In addition, SERF2 can induce huntingtin aggregation in SK-N-SH neuroblastoma cells. (PMID:20723760)

Bioinformatics

Entrez	10169 Human
Uniprot	P84101 Human
Product By Gene ID	10169
Alternate Names	4F5rel FAM2CFLJ38557,4F5REL FLJ20431 FLJ37527 Gastric cancer-related protein VRG107 H4F5REL HsT17089 MGC48826 Protein 4F5-related small EDRK-rich factor 2

Research Areas for SERF2

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Neuroscience