SECISBP2 Products

Description

SECISBP2 is an RNA binding protein that interacts with the Sec insertion sequence (SECIS) element in selenoprotein mRNAs. The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. Mutations in the SECISBP2 gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism.

Bioinformatics

Entrez	79048 Human
Uniprot	AAH36109.1 Human NP_076982 Human NP_076982.3 Human
Product By Gene ID	79048
Alternate Names	DKFZp686C09169 SBP2SECIS-binding protein 2 SECIS binding protein 2 selenocysteine insertion sequence binding protein 2 selenocysteine insertion sequence-binding protein 2