Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Monoclonal
Species: Hu
Applications: WB
Description
SDHC encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria. The encoded protein is one of two integral membrane proteins that anchor other subunits of the complex, which form the catalytic core, to the inner mitochondrial membrane. Several related pseudogenes are located in different genomic regions. Mutations in this gene have been associated with paragangliomas. Alternatively spliced transcript variants encoding different isoforms have been described.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human |
Product By Gene ID |
6391 |
Alternate Names |
- Integral membrane protein CII-3
- mitochondrial
- PGL3
- QPs1
- QPs-1
- SDH3
- succinate dehydrogenase complex, subunit C, integral membrane protein, 15kD
- succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
- succinate-ubiquinone oxidoreducatase cytochrome B large subunit
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