S100A/B Products

S100A/B Antibody (D28-E)
S100A/B Antibody (D28-E)
Species: Hu
Applications: IHC, IHC-Fr, IHC-P
Host: Rabbit Monoclonal
S100A/B Antibody
S100A/B Antibody
Species: Hu, Bv
Applications: WB, IHC, IHC-Fr, IHC-P
Host: Rabbit Polyclonal


S100 belongs to the family of calcium binding proteins such as calmodulin and troponin C. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. S100 protein may function in stimulation of Ca2+ induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. Immunoreactive S100 protein localizes in the cytoplasm and nuclei of astrocytes, Schwann's cells, ependymomas and astrogliomas. Ganglion cells do not stain for S100 protein. S100 can be detected in almost all benign naevi and malignant melanocytic tumors of the skin, and in Langerhans cells in the skin.


Entrez Human
Uniprot Human
Product By Gene ID 6271
Alternate Names
  • S100 protein, alpha polypeptide
  • S-100 protein alpha chain
  • S100 alpha
  • S100A
  • protein S100-A1
  • S100-alpha
  • S100 calcium-binding protein A1S100
  • S-100 protein subunit alpha
  • S100 calcium binding protein A1

Research Areas for S100A/B

Find related products by research area and learn more about each of the different research areas below.

Astrocyte Markers
Breast Cancer
Cell Biology
Cytoskeleton Markers
Neuronal Cell Markers

Bioinformatics Tool for S100A/B

Discover related pathways, diseases and genes to S100A/B. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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