RNPC1 Products

Description

RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2

Bioinformatics

Entrez	55544 Human
Uniprot	NP_059965 Human NP_059965.2 Human NP_906270 Human Q9H0Z9 Human
Product By Gene ID	55544
Alternate Names	CLL-associated antigen KW-5 HSRNASEBRRM) containing 1 RNA binding motif protein 38 RNA-binding motif protein 38 RNA-binding protein 38 RNA-binding region containing protein 1 RNA-binding region-containing protein 1 SEB4 seb4B ssDNA binding protein SEB4 ssDNA-binding protein SEB4