RGS4 Products

Description

Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120 amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37% identical to RGS1 and 97% identical to rat RGS4. This protein negatively regulates signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm.

Bioinformatics

Entrez	19736 Mouse 29480 Rat 5999 Human
Uniprot	AAH51869 Human NM_005613 Human NP_005604 Human P49798 Human
Product By Gene ID	5999
Alternate Names	DKFZp761F1924 MGC2124 MGC60244 regulator of G-protein signaling 4 regulator of G-protein signalling 4 RGP4 schizophrenia disorder 9 SCZD9

Research Areas for RGS4

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction