Species: Hu, Mu, Rt
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Species: Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Bv
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, PA, PAGE, AP
Species: Hu
Applications: AC
Description
Rap1GAP, an 85/95kDa protein, is a member of a family of GAP's specific for Rap1 (1). Though to be an important tumor suppressor, Rap1GAP has no sequence homology with other GAPs such as RasGAP, RanGAP and RhoGAP. Purified as a cytosolic and membrane-bound protein, both isoforms consist of two monomers each contain a dimerization and a catalytic domain (2-4). Mutations in the GAP domain of the tumor suppressor tuberin, can cause benign tumor phenotype tuberous sclerosis (5).
Bioinformatics
Entrez |
Mouse Rat Human |
Uniprot |
Human Human Human Human |
Product By Gene ID |
5909 |
Alternate Names |
- GTPase activating protein 1
- RAP1 GTPase activating protein
|
Research Areas for RAP1GAP
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Cellular MarkersLysosome Markers
Bioinformatics Tool for RAP1GAP
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Bioinformatics Tool Guide for instructions on using this tool.