Rab4 Products

Antibodies
Rab4 Antibody
Rab4 Antibody
NB100-74519
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Rab4 Antibody (4E11)
Rab4 Antibody (4E11)
NBP2-37485
Species: Hu, Mu, Pm
Applications: WB, ELISA, Flow, IHC
Host: Mouse Monoclonal
Rab4 Antibody (1C10)
Rab4 Antibody (1C10)
H00005867-M01
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
Lysates
Rab4 Overexpression Lysate (D ...
Rab4 Overexpression Lysate (Denatu...
H00005867-T01
Species: Hu
Applications: WB
Rab4 Overexpression Lysate (N ...
Rab4 Overexpression Lysate (Native)
NBL1-15080
Applications: WB
Proteins
Rab4 Recombinant Protein
Rab4 Recombinant Protein
NBP1-72350
Species: Hu
Applications: PAGE
RNAi
Rab4 RNAi
Rab4 RNAi
H00005867-R01V
Species: Hu
Applications: WB, RNAi, RNAi SP
Rab4 RNAi
Rab4 RNAi
H00005867-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Rab4 is a small GTPase that regulates recycling of proteins, such as GPCRs, from the early endosomes to the cell surface. Overexpression of Rab4 causes a redistribution of receptors on plasma membrane versus endocytic compartments. Rab4 is also involved in the translocation of glucose transporter (Glu4) in adipocytes in response to insulin. Association of Rab4 with transferrin receptor containing early endosomes is mediated through the geranylgeranyl groups at its carboxyl terminus. Rab4 can be used as a marker for early endosomes (see Daro et al. 1996 and Zuk et al. 1999 for more information). Membrane association is also cell cycle dependent, as phosphorylation at its C-terminal cdc2 kinase consensus sequence in mitotic cells leads to dissociation of Rab4 into the cytosol.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 5867
Alternate Names
  • ras-related protein Rab-4A
  • RAB4, member RAS oncogene family
  • Oncogene RAB4
  • RAB4HRES-1/RAB4
  • RAB4A, member RAS oncogene family

Research Areas for Rab4

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction

Bioinformatics Tool for Rab4

Discover related pathways, diseases and genes to Rab4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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