PTPRH Products

Description

The protein encoded by the PTPRH gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. The extracellular region contains eight fibronectin type III-like repeats and multiple N-glycosylation sites. The gene was shown to be expressed primarily in brain and liver, and at a lower level in heart and stomach. It was also found to be expressed in several cancer cell lines, but not in the corresponding normal tissues. Alternative splicing results in multiple transcript variants. (provided by RefSeq)

Bioinformatics

Product By Gene ID	5794
Alternate Names	EC 3.1.3.48 FLJ39938 MGC133058 MGC133059 protein tyrosine phosphatase, receptor type, H receptor-type tyrosine-protein phosphatase H R-PTP-H SAP1 SAP-1 Stomach cancer-associated protein tyrosine phosphatase 1 Transmembrane-type protein-tyrosine phosphatase type H