PTIP Products

Description

PTIP facilitates ATM-mediated activation of p53 and promotes cellular resistance to ionizing radiation. Tandem BRCT (BRCA1 carboxyl-terminal) domains in PTIP and in BRCA1 serve as phosphoserine or phosphothreonine specific binding modules that recognize substrates phosphorylated by the kinases ATM and ATR in response to gamma irradiation.

Bioinformatics

Entrez	22976 Human
Uniprot	AAH33781.1 Human NM_007349 Human NP_031375.3 Human NP_620176 Human Q6ZW49 Human
Product By Gene ID	22976
Alternate Names	CAGF28 PACIP1 PAX interacting (with transcription-activation domain) protein 1 PAX transactivation activation domain-interacting protein PAX transcription activation domain interacting protein 1 like PAX-interacting protein 1 PAXIP1LCAGF29 protein encoded by CAG trinucleotide repeats PTIPFLJ41049 TNRC2

Research Areas for PTIP

Find related products by research area and learn more about each of the different research areas below.

Cancer
DNA Repair