PROP1 Products

Description

PROP1 has both DNA-binding and transcriptional activation ability. Its expression leads to ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes, and caudomedial thyrotropes. Inactivating mutations in PROP1 result in deficiencies of luteinizing hormone (LH; MIM 152780), follicle-stimulating hormone (FSH; MIM 136530), growth hormone (GH; MIM 139250), prolactin (PRL; MIM 176760), and thyroid-stimulating hormone (TSH; MIM 188540). See combined pituitary hormone deficiency (CPHD; MIM 262600).[supplied by OMIM]

Bioinformatics

Product By Gene ID	5626
Alternate Names	CPHD2 homeobox protein prophet of Pit-1 Pituitary-specific homeodomain factor PROP paired-like homeobox 1 PROP-1 prophet of Pit1, paired-like homeodomain transcription factor

Research Areas for PROP1

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cell Biology